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Am J Perinatol 2017; 34(01): 44-50
DOI: 10.1055/s-0036-1584138
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

A New IVH Scoring System Based on Laterality Enhances Prediction of Neurodevelopmental Outcomes at 3 Years Age in Premature Infants

Mountasser Al-Mouqdad
1   Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
,
Sameer Al-Abdi
2   Department of Pediatrics, King Abdulaziz Hospital, Ministry of National Guard, Al-Ahsa, Saudi Arabia
,
James N. Scott
3   Alberta Health Services, Alberta, Canada
4   Department of Diagnostic Imaging, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
,
Alison Hurley
3   Alberta Health Services, Alberta, Canada
4   Department of Diagnostic Imaging, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
,
Selphee Tang
3   Alberta Health Services, Alberta, Canada
,
Dianne Creighton
3   Alberta Health Services, Alberta, Canada
5   Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada
,
Khorshid Mohammad
1   Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
3   Alberta Health Services, Alberta, Canada
,
Majeeda Kamaluddeen
1   Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
3   Alberta Health Services, Alberta, Canada
,
Abhay Lodha
1   Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
3   Alberta Health Services, Alberta, Canada
5   Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada
6   Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
› Author Affiliations
Further Information

Publication History

01 March 2016

29 March 2016

Publication Date:
16 May 2016 (online)

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Abstract

Objective To compare the new intraventricular hemorrhage (IVH) Abdi score to the Papile grading system of IVH for prediction of composite outcome of death or neurodevelopmental impairment (NDI).

Methods In a cohort study, all preterm infants with IVH who were born ≤1,250 g and/or ≤ 28 weeks of gestation at birth were prospectively followed up in our neonatal follow-up clinic. All cranial ultrasounds of the included infants were reviewed by neuroradiologists who were blinded to the clinical data and neurodevelopmental outcomes. Cranial ultrasounds were graded according to the Papile scoring system and by calculation of the Abdi score.

Results A total of 183 preterm infants met inclusion and exclusion criteria. Of these, 80 (44%) had the composite primary outcome of death or NDI (51 died, 29 survived with NDI). The area under receiver operating characteristic curve for predicting death or NDI was 0.87 (95% confidence interval [CI]: 0.81–0.93) for Abdi score and 0.85 (95% CI: 0.79–0.91) for Papile grading (p = 0.04). Abdi scores had higher specificity than Papile grade II at Abdi score 5 (63.9 vs. 39.2%; p < 0.001) and Abdi score 6 (73.2 vs. 39.2%; p < 0.001).

Conclusion Abdi scores seem to be more specific than Papile grading system in predicting death or NDI by 3 years' corrected age.

Keywords

neurodevelopmental impairment - intraventricular hemorrhage - preterm infants

Supplementary Material

 

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