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Semin Neurol 2016; 36(04): 317-323
DOI: 10.1055/s-0036-1586261
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Stroke: New Developments and Their Application in Clinical Practice

Peter J. Kelly
1   Department of Neurology, Mater Misericordiae University Hospital, Dublin, Ireland
,
Eoin Kavanagh
2   Department of Radiology, Mater Misericordiae University Hospital, Dublin, Ireland
,
Sean Murphy
3   Department of Stroke Medicine, Mater Misericordiae University Hospital, Dublin, Ireland
› Author Affiliations
Further Information

Publication History

Publication Date:
19 September 2016 (online)

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Abstract

Significant advances have been made in recent years in primary stroke prevention, improved stroke outcomes in high-income populations, emergency stroke therapy, and stroke prevention. In this article, we review recent trends in stroke epidemiology, improvements in delivery of intravenous thrombolysis (via stroke system-wide approaches, application of ‘Lean Principles’ to improve workflow processes, and re-evaluation of exclusion criteria), recent stroke thrombectomy trials, and new developments in stroke prevention, with emphasis on risk prediction in transient ischemic attack, choice and timing of anticoagulation therapy for secondary stroke prevention, and emerging concepts in risk stratification for management of symptomatic carotid stenosis.

Keywords

stroke - population - therapy - atrial fibrillation - transient ischaemic attack - prevention
 

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