Chiral Gold Complex Catalyzed Tandem Dehydrative Cyclization/Hetero-Diels–Alder Reaction

Abstract

A tandem dehydrative cyclization/aza-hetero-Diels–Alder reaction catalyzed by gold(I) complex bearing BINOL-derived chiral phosphoramidite ligand has been developed. With this method, optically active chiral bicyclic tetrahydropyridazine derivatives could be obtained in one step from readily available starting materials.

Key words

asymmetric gold catalysis - tandem reaction - hetero-Diels–Alder reaction

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