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Synthesis 2018; 50(05): 1090-1096
DOI: 10.1055/s-0036-1591843
DOI: 10.1055/s-0036-1591843
paper
Potassium Carbonate Promoted C–N Coupling Reaction between Benzamides and Aryl Iodides
We would like to gratefully acknowledge financial support from the A Project Funded by the Priority Academic Program for the Development of Jiangsu Higher Education Institutions and the National Natural Science Foundation of China (No. 21072143).Further Information
Publication History
Received: 01 September 2017
Accepted after revision: 03 November 2017
Publication Date:
23 November 2017 (online)
Abstract
A practical and efficient method for N-arylation of benzamides promoted by potassium carbonate in the presence of DMEDA was developed. The reaction was carried out without addition of any transition-metal catalyst to afford a variety of N-arylated products in moderate to good yields (up to 97%).
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1591843. 1H and 13C NMR spectra for all compounds are included.
- Supporting Information
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