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Synthesis 2018; 50(11): 2231-2234
DOI: 10.1055/s-0037-1609446
DOI: 10.1055/s-0037-1609446
paper
An Efficient Oxidation of Sulfides to Sulfones with Urea–Hydrogen Peroxide in the Presence of Phthalic Anhydride in Ethyl Acetate
This work was supported by Regis Technologies, Inc.Further Information
Publication History
Received: 27 February 2018
Accepted after revision: 14 March 2018
Publication Date:
04 April 2018 (online)
Abstract
A metal-free, environmentally benign oxidation of substituted sulfides directly to their corresponding sulfones is described. Using urea-hydrogen peroxide and phthalic anhydride in ethyl acetate clean conversion into the sulfone was achieved without observation of the possible sulfoxide oxidation product.
Key words
sulfones - sulfoxides - sulfide oxidation - urea–hydrogen peroxide - UHP - phthalic anhydrideSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0037-1609446.
- Supporting Information
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