The azacycloalkane 1-azocan-5-one is embedded in the structure of several products of natural origin displaying a variety of bioactivities. Two convenient and straightforward routes were developed to synthesize N-Boc-azocan-5-one from readily available raw materials featuring a ring-closing metathesis (RCM) reaction as the key step.
Key words
azocanone - nitrogen heterocycles - ring-closing metathesis - synthesis
