Recent Developments in Direct C–H Functionalization of Quinoxalin-2(1H)-ones via Radical Addition Processes

Monika Monika; Sermadurai Selvakumar

doi:10.1055/s-0037-1611910

Synthesis, Inhaltsverzeichnis

Synthesis 2019; 51(22): 4113-4136
DOI: 10.1055/s-0037-1611910

review

Recent Developments in Direct C–H Functionalization of Quinoxalin-2(1H)-ones via Radical Addition Processes

Monika Monika

^aDepartment of Chemistry, School of Chemical Sciences, Central University of Haryana, Mahendergarh-123031, Haryana, India

,

Sermadurai Selvakumar ∗

^aDepartment of Chemistry, School of Chemical Sciences, Central University of Haryana, Mahendergarh-123031, Haryana, India

^bDiscipline of Chemistry, Indian Institute of Technology Indore, Simrol Indore-453552, Madhya Pradesh, India eMail: selva@iiti.ac.in

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Abstract

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Dedicated to Professor Vinod K. Singh, IIT Kanpur on the occasion of his 60^th birthday

Abstract

This review article covers the recent developments in direct C–H functionalization of quinoxalin-2(1H)-one derivatives via radical additions at the C3 position. Reaction types have been categorized depending on the kind of radical used, with representative examples and insightful mechanistic details provided.

1 Introduction

2 Reactions with Alkyl Radicals

3 Reactions with Acyl Radicals

4 Reactions with Aryl Radicals

5 Reactions with Perfluoroalkyl Radicals

6 Reactions with Alkoxycarbonyl Radicals

7 Reactions with Nitrogen Radicals

8 Reactions with Oxygen Radicals

9 Reactions with Phosphorus Radicals

10 Conclusion

Key words

C–H functionalization - quinoxalin-2(1H)-ones - visible light photocatalysis - radicals - oxidants

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Referenzen

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