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Thromb Haemost 2002; 88(01): 159-160
DOI: 10.1055/s-0037-1613171
DOI: 10.1055/s-0037-1613171
Letters to the Editor
Discrepancies in Measured Factor VIII Activity in Patients Treated with Factor VIII Concentrate of Human or Porcine Origin
Further Information
Publication History
Received
05 November 2001
Accepted after revision
28 February 2002
Publication Date:
09 December 2017 (online)
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References
- 1 Keeling DM, Sukhu K, Kemball-Cook G, Waseem N, Bagnall R, Lloyd JV. Diagnostic importance of the two-stage factor VIII:C assay demonstrated by a case of mild haemophilia associated with His1954 → Leu substitution in the factor VIII A3 domain. Br J Haematol 1999; 105: 1123-26.
- 2 Schwaab R, Oldenburg J, Kemball-Cook G, Albert T, Juhler C, Hanfland P. Ingerslev J. Assay discrepancy in mild haemophilia A due to a factor VIII missense mutation (Asn694Ile) in a large Danish family. Br J Haematol 2000; 109: 523-28.
- 3 Roelse JC, De Laaf RTM, Mertens K, Van Mourik JA, Oldenburg J. Voorberg J. Altered sensitivity towards factor IXa explains assay discrepancies in plasma of haemophilia A patients with a GLU720LYS substitution in factor VIII. Thromb Haemost 1999; 82: 5a.
- 4 Lollar P, Parker ET. Structural basis for the decreased procoagulant activity of human factor VIII compared to the porcine homolog. J Biol Chem 1991; 266: 12481-86.
- 5 Aronson DL, Chang P. Activated factor VIII in therapeutic preparations: Analysis by ultracentrifugation. Vox Sang 1996; 71: 142-49.
- 6 Hay CRM, Bolton-Maggs P. Porcine factor VIIIC in the management of patients with factor VIII inhibitors. Transfus Med Rev 1991; 05: 145-51.