Subscribe to RSS
DOI: 10.1055/s-0037-1613261
High Prevalence of Asymptomatic Deep Vein Thrombosis on Admission in a Medical Unit among Elderly Patients
The TADEUS Project Supported by Ministere de l’Emploi et de la Solidarite (Projet Hospitalier de Recherche Clinique 1998)Publication History
Received
23 January 2002
Accepted after resubmission
26 June 2002
Publication Date:
09 December 2017 (online)
Summary
The prevention of venous thromboembolism in medical patients remains questioned. All consecutive outpatients admitted in our medical unit were considered for inclusion in this study which aimed to estimate the prevalence of asymptomatic venous thrombosis on admission and the incidence during hospital stay. Exclusion criteria were: age <18 years, suspicion of venous thromboembolism, stay <4 days, ongoing anticoagulant therapy. Venous compression ultrasonography of the lower limbs was performed within 48 h. 234 patients were included. The prevalence of asymptomatic deep vein thrombosis on admission and the incidence during hospital follow-up were respectively 5.5% (95% confidence interval, 3.1 to 9.5%) and 2.6 per 1000 person-days (95% confidence interval, 0.0 to 5.2). The prevalence and the incidence reached respectively 17.8% (95% confidence interval, 8.5 to 32.6%) and 6.0 per 1000 person-days (95% confidence interval, 0.0 to 12.7) among patients over 80 years. A high prevalence of asymptomatic deep vein thrombosis on admission was suggested particularly among elderly medical patients.
-
References
- 1 Oger E. Incidence of venous thromboembolism: a community-based study in Western France. EPI-GETBO Study Group. Groupe d’Etude de la Thrombose de Bretagne Occidentale. Thromb Haemost 2000; 83: 657-60.
- 2 Leizorovicz A, Haugh MC, Chapuis FR, Samama MM, Boissel JP. Low molecular weight heparin in prevention of perioperative thrombosis. BMJ 1992; 305: 913-20.
- 3 Clagett GP, Anderson Jr FA, Geerts W, Heit JA, Knudson M, Lieber-man JR. et al. Prevention of venous thromboembolism. Chest 1998; 114 (Suppl. 05) Suppl): 531S-60S.
- 4 Couturaud F, Leroyer C, Le Moigne E, Oger E, Mottier D. Prevention de la thrombose veineuse profonde en milieu medical. Presse Med 1996; 25: 1935-40.
- 5 Risk of and prophylaxis for venous thromboembolism in hospital patients. Thromboembolic Risk Factors (THRIFT) Consensus Group. BMJ 1992; 305: 567-74.
- 6 Hirsh J, Hull RD, Raskob GE. Epidemiology and pathogenesis of venous thrombosis. J Am Coll Cardiol 1986; 08 (6 Suppl B): 104B-13B.
- 7 Anderson Jr FA, Wheeler HB, Goldberg RJ, Hosmer DW, Forcier A. The prevalence of risk factors for venous thromboembolism among hospital patients. Arch Intern Med 1992; 152: 1660-4.
- 8 Lane DA, Mannucci PM, Bauer KA, Bertina RM, Bochkov NP, Boulyjen-kov V. et al. Inherited thrombophilia: Part 1. Thromb Haemost 1996; 76: 651-62.
- 9 Bressollette L, Nonent M, Oger E, Garcia JF, Larroche P, Guias B. et al. Diagnostic accuracy of compression ultrasonography for the detection of asymptomatic deep venous thrombosis in medical patients. The TADEUS Project. Thromb Haemost 2001; 86: 529-33.
- 10 Oger E, Leroyer C, Bressollette L, Nonent M, Le Moigne E, Bizais Y. et al. Evaluation of a new, rapid, and quantitative D-Dimer test in patients with suspected pulmonary embolism. Am J Respir Crit Care Med 1998; 158: 65-70.
- 11 Samama MM, Cohen AT, Darmon JY, Desjardins L, Eldor A, Janbon C. et al. A comparison of enoxaparin with placebo for the prevention of venous thromboembolism in acutely ill medical patients. Prophylaxis in Medical Patients with Enoxaparin Study Group. N Engl J Med 1999; 341: 793-800.
- 12 Prescott SM, Richards KL, Tikoff G, Armstrong Jr JD, Shigeoka JW. Venous thromboembolism in decompensated chronic obstructive pulmonary disease. A prospective study. Am Rev Respir Dis 1981; 123: 32-6.
- 13 Schonhofer B, Kohler D. Prevalence of deep-vein thrombosis of the leg in patients with acute exacerbation of chronic obstructive pulmonary disease. Respiration 1998; 65: 173-7.