Absence of Factor V Leiden Mutation and Low Prothrombin G 20210 A Mutation Prevalence in a Healthy Moroccan Population

Florence Mathonnet; Sellama Nadifi; Valérie Serazin-Leroy; Mbarka Dakouane; Yves Giudicelli

doi:10.1055/s-0037-1613361

Thrombosis and Haemostasis, Inhaltsverzeichnis

Thromb Haemost 2002; 88(06): 1073-1074
DOI: 10.1055/s-0037-1613361

Letters to the Editor

Schattauer GmbH

Absence of Factor V Leiden Mutation and Low Prothrombin G 20210 A Mutation Prevalence in a Healthy Moroccan Population

Florence Mathonnet

¹Department of Biochemistry and Molecular Biology, Medical Faculty Paris-Ouest, University Paris V, CHI Poissy Cedex, France

,

Sellama Nadifi

²Laboratory of Human Genetics, Medical Faculty of Casablanca, University Hassan II, Morocco

,

Valérie Serazin-Leroy

¹Department of Biochemistry and Molecular Biology, Medical Faculty Paris-Ouest, University Paris V, CHI Poissy Cedex, France

,

Mbarka Dakouane

¹Department of Biochemistry and Molecular Biology, Medical Faculty Paris-Ouest, University Paris V, CHI Poissy Cedex, France

,

Yves Giudicelli

¹Department of Biochemistry and Molecular Biology, Medical Faculty Paris-Ouest, University Paris V, CHI Poissy Cedex, France

References
1 Ridker PM, Hennekens CH, Lindpaintner K, Stampfer MJ, Eisenberg PR, Miletich JP. Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men. N Engl J Med 1995; 332: 912-7.
2 Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3' -untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996; 88: 3698-703.
3 Rees DC. The population genetics of factor V Leiden (Arg 506 Gin). Br J Haematol 1996; 95: 579-86.
4 Rees DC, Chapman NH, Webster MT, Guerreiro JF, Rochette J, Clegg JB. Born to clot: the European burden. Br J Haematol 1999; 105: 564-6.
5 Rees DC, Cox M, Clegg JB. World distribution of factor V Leiden. Lancet 1995; 346: 1133-4.
6 Gurgey A, Rustemov R, Parlak H, Balta G. Prevalence of factor V Leiden and Methylenetetrahydrofolate Reductase C677T mutations in Azerbaijan. Thromb Haemost 1998; 80: 520-1.
7 Togrul J, Rustemov R, Gurgey A, Altay S, Altay C. Prevalence of the prothrombin gene G20210A mutation in Azerbaijan. Br J Haematol 2000; 108: 887-8.
8 Gurgey A, Kudayarov DK, Tuncer M, Parlak H, Altay C. The factor V Leiden and prothrombin G20210A mutations in Kirghiz population. Thromb Haemost 2000; 84: 356.
9 Ozbek U, Tangiin Y. Frequency of factor V Leiden (Arg506Gln) in Turkey. Br J Haematol 1997; 97: 504-5.
10 Gurgey A, Hicsomnez G, Parlak H, Balta G, Celiker A. The prothrombin gene 20210 G-A mutation in Turkish patients with thrombosis. Am J Hematol 1999; 59: 179-80.
11 Seligsohn U, Zivelin A. Thrombophilia as a multigenic disorder. Thromb Haemost 1997; 78 (01) 297-301.
12 Awidi A, Shannak M, Bseiso A, Kailani MAM, Kailani MA, Omar N, Anshasi B, Sakarneh N. High prevalence of factor V Leiden in healthy Jordanian arabs. Thromb Haemost 1999; 81: 582-4.
13 Rosen E, Renbaum P, Heyd J, Levy-Lahad E. High frequency of factor V Leiden in a population of Israeli Arabs. Thromb Haemost 1999; 82 (06) 1768.
14 Dzimiri N, Meyer B. World distribution of factor V Leiden. Lancet 1996; 347: 481-2.
15 Hammoud DF, Eldibanny MM, Nowak JA. Prevalence of the factor V Leiden mutation in the Egyptian population. (Abstract). Blood 1996; 88 (10) (Suppl. 01) 73b.
16 Chafa O, Reghis A, Aubert A, Fischer AM. Prevalence of the FVQ506 (factor V Leiden) mutation in the normal and thrombophilic Algerian population. Br J Haematol 1997; 97: 688-9.
17 Helley D, Chafa O, Yaker NJ, Reghis A, Fischer AM. Prevalence of the prothrombin gene 20210A mutation in thrombophilic and healthy Algerian subjects. Thromb Haemost 1999; 82: 1554-5.
18 Gandrille S, Alhenc-Gelas M, Aiach M. A rapid screening method for the factor V Arg 506 Gin mutation. Blood Coag Fibrinol 1995; 06: 245-9.
19 Alhenc-Gelas M, Arnaud E, Nicaud V, Aubry ML, Fiessinger JN, Aiach M, Emmerich J. Venous thromboembolic disease and the prothrombin methylene tetrahydrofolate reductase and factor V genes. Thromb Haemost 1999; 81: 506-10.
20 Zivelin A, Griffin JH, Xu X, Pabinger I, Samama M, Conard J, Brenner B, Eldor A, Seligsohn U. A single genetic origin for a common Caucasian risk factor for venous thrombosis. Blood 1997; 02: 397-402.
21 Rosendaal FR, Doggen CJ, Zivelin A, Arruda VR, Aiach M, Siscovick DS, Hillarp A, Watzke HH, Bernardi F, Cumming AM, Preston FE, Reitsma PH. Geographic distribution of the 20210 G to A prothrombin variant. Thromb Haemost 1998; 79: 706-8.
22 Zheng H, Tzeng CC, Butt C, Randell E, Xie YG. An extremely low prevalence of factor V Leiden, FIIG20210A and FXIIIV34L in Taiwan Chinese population. Thromb Haemost 2002; 87: 1081-2.
23 Dilley A, Austin H, Hooper WC, El-Jamil M, Whitsett C, Wenger NK, Benson J, Evatt B. Prevalence of the prothrombin 20210 G-to-A variant in blacks: infants, patients with venous thrombosis, patients with myocardial infarction, and control subjects. J Lab Clin Med 1998; 132: 452-5.