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Thromb Haemost 1998; 80(01): 181-185
DOI: 10.1055/s-0037-1615160
Rapid Communication
Schattauer GmbH

Development and Practical Use of the New Quantitative Bleeding Time Test Apparatus

Yoshiko Tamai
From the First Department of Internal Medicine, Hirosaki University School of Medicine, Hirosaki, Japan
,
Hideki Takami
From the First Department of Internal Medicine, Hirosaki University School of Medicine, Hirosaki, Japan
,
Rieko Nakahata
From the First Department of Internal Medicine, Hirosaki University School of Medicine, Hirosaki, Japan
,
Yuka Nakui
From the First Department of Internal Medicine, Hirosaki University School of Medicine, Hirosaki, Japan
,
Tomoaki Akagi
From the First Department of Internal Medicine, Hirosaki University School of Medicine, Hirosaki, Japan
,
Akihiro Munakata
From the First Department of Internal Medicine, Hirosaki University School of Medicine, Hirosaki, Japan
› Author Affiliations
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Publication History

Received 05 May 1997

Accepted after resubmission 10 March 1998

Publication Date:
08 December 2017 (online)

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Summary

We have developed a new computerized system for measurement of quantitative bleeding time (QBT) to detect subtle abnormalities of primary hemostasis that are difficult to detect with the standard bleeding time determination. This new apparatus can simultaneously measure the bleeding time (BT; sec), amount of total blood loss (Tv; μl), maximum bleeding rate (Rmax; μl/sec) and bleeding pattern from the bleeding time incision. We have also developed a new holder for the Simplate that enables more consistent incisions and thus improves the reproducibility of the BT test.

In this study, the newly developed QBT test was performed in 137 normal healthy volunteers and 10 patients having defined abnormalities of either primary or secondary hemostasis. Comparisons of the standard BT test and our QBT were made in 5 normal subjects and 7 thrombocytopenic patients. Additionally, 6 normal subjects were examined with both tests before and after administration of aspirin. Those results show that our QBT appears to be a more sensitive indicator of primary hemostasis than the standard BT method.

 

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