Ulcera crurum bei Kryoglobulinämie und Hepatitis C

Zusammenfassung

Die Ursachenfindung eines therapieresistenten Ulcus cruris ist und bleibt eine Herausforderung. Wir berichten über Kryoglobulinämie als Ursache von schmerzhaften Ulcera crurum einer 73-jährigen Patientin mit bekannter Hepatitis- C-Virus-Infektion. Kryoglobuline sind eine häufige Begleiterscheinung einer Hepatitis-C-Virus-Infektion und können über vaskulitische Prozesse mit Blasenbildung bis hin zu Ulzerationen eine wichtige Rolle in der Pathogenese des Ulcus cruris spielen.

Summary

Finding out the cause of chronic leg ulcers is always a diagnostic challenge. We report on a 73-year-old lady with cryoglobulinaemia, painful leg ulcers and known hepatitis C virus infection. Cryoglobulins are often present in a hepatitis C virus infection and can cause widespread vasculitis, which may progress to blistering and frank ulceration. Therefore, in the pathogenesis of leg ulcers, cryoglobulins can play an important role.

Résumé

La recherche de la cause d’un ulcère crural réfractaire à la thérapie constitue un défi. Nous rapportons un cas de cryoglobulinémie comme cause d’un ulcère crural douloureux chez une patiente de 73 ans atteinte d’une infection à virus de l’hépatite C avérée. Les cryoglobulines constituent une manifestation associée fréquente d’une infection à virus de l’hépatite C et peuvent jouer un rôle important dans la pathogenèse de l’ulcère crural par les processus vasculitiques avec formation de vésicules pouvant aller jusqu’aux ulcérations.

Schlüsselwörter

Kryoglobulinämie - Hepatitis C - Ulcus cruris - Rheumafaktor

Keywords

Cryoglobulinaemia - hepatitis C - leg ulcers - rheumatoid factors

Mots clés

Cryoglobulinémie - hépatite C - ulcère crural - facteur rhumatismal

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