PDF herunterladen
Nuklearmedizin 1972; 11(01): 24-36
DOI: 10.1055/s-0038-1624770
Originalarbeiten — Original Articles — Travaux Originaux
Schattauer GmbH

The Blood and Urinary Clearance of 203Hg-Chlormerodrin in Renal Insufficiency

Die Blut- und Harnclearance von 203Hg-Chlormerodrin bei NiereninsuffizienzLa clearance sanguine et minaire du 203Hg Chloromerodrine dans l’insuffisance rénale
J. S. Bajaj   *
1   Radio Isotope Unit. All-india Institute of Medical Sciences, New Delhi
,
R. C. Bhat   *
1   Radio Isotope Unit. All-india Institute of Medical Sciences, New Delhi
,
A. K. Basu   **
1   Radio Isotope Unit. All-india Institute of Medical Sciences, New Delhi
,
J. S. Guleria   *
1   Radio Isotope Unit. All-india Institute of Medical Sciences, New Delhi
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Received:24. November 1971

Publikationsdatum:
24. Januar 2018 (online)

    Lizenzen und Reprints

Summary

Studies performed on patients with renal disease, with and without significant renal insufficiency, have shown a statistically significant difference in the blood clearance and urinary excretion of 203Hg-Chlormerodrin in these two groups. An attempt has been made to correlate these two parameters with the endogenous creatinine clearance.

Untersuchungen bei nierenerkrankten Patienten mit und ohne deutliche Niereninsuffizienz zeigten statistisch signifikante Unterschiede in der Blutclearance und der Harnausscheidung von 203Hg-Chlormerodrin. Es wurde versucht, diese beiden Parameter mit der endogenen Kreatinin-Clearance zu korrelieren.

Des examens dans des malades souffrant d’une rénopathie avec et sans insuffisance rénale montraient d’appréciables differences statistiques entre la clearance sanguine et urinaire de la Chloromerodrine. On a essayé de coordiner ces deux paramètres avec la clearance de la créatinine endogène.

* Department of Medicine.


** Radio Isotope Unit. All-india Institute of Medical Sciences, New Delhi-16, India.


 

  • References

  • 1 Buse M. G., Sibrans D. F., Buse J.. Scintillation Scanning of Kidneys: A Pitfall of Interpretation in Renal Insufficiency. Ann. Intern. Med 1964; 60: 857-865.
    CrossrefPubMedGoogle Scholar
  • 2 Borghgraef R. R. M., Pitts R. F.. The Distribution of Chlormerodrin (Neohydrin) in Tissues of the Rat and Dog. J. Clin. Invest 1956; 35: 31-43.
    CrossrefPubMedGoogle Scholar
  • 3 Bajaj J. S., Basu A. K., Bhat R. C., Guleria J. S.. Chlormerodrin Accumulation Test – A procedure for the assessment of differential renal function. Indian J. Med. Res 1971; 59: 1270-1274.
    PubMedGoogle Scholar
  • 4 Greenlaw R. H., Quaife M.. Retention of Neohydrin 203Hg as determined with a total Body Scintillation Counter. Radiology 1962; 78: 970-973.
    CrossrefPubMedGoogle Scholar
  • 5 Reba R. C., McAfee J. G., Wagher Jr. H. N.. Radiomercury-Labelled Chlormerodrin for in vivo uptake studies and Scintillation Scanning of unilateral renal lesions associated with hypertenison. Medicine 1963; 42: 269-296.
    CrossrefPubMedGoogle Scholar
  • 6 Threefoot S. A., Ray C. T., Busch G. E.. et al. Concentration-time course in the plasma of Man of Radiomercury introduced as a mercurial diuretic. J. Clin. Invest 1949; 28: 661-670.
    PubMedGoogle Scholar