Download PDF
Schlaf 2014; 03(04): 200-205
DOI: 10.1055/s-0038-1626117
Review
Schattauer GmbH

Aktuelle Aspekte der Schichtarbeit

Was wissen wir wirklich?
Thomas Erren
1   MPH, Direktor des Instituts und der Poliklinik für Arbeitsmedizin, Umweltmedizin und Präventionsforschung der Universität zu Köln, Kerpener Str. 62, 50937 Köln, Email: tim.erren@uni-koeln.de
,
Andreas Pinger
2   MPH, Institut und Poliklinik für Arbeitsmedizin, Umweltmedizin und Präventionsforschung der Universität zu Köln
,
Valérie Gross
3   Institut und Poliklinik für Arbeitsmedizin, Umweltmedizin und Präventionsforschung der Universität zu Köln ©Medizin Foto Köln
› Author Affiliations
Further Information

Publication History

Publication Date:
10 February 2018 (online)

    Permissions and Reprints

Gemäß des Statistischen Amtes der Europäischen Union (Eurostat) (1) leisteten im Jahr 2013 rund 17 % der Beschäftigen in Deutschland Schichtdienst, 1992 waren es noch 11,5 %. Infolge der Unverzichtbarkeit von Schichtarbeit und der Anzahl an Betroffenen durch Arbeit zu chronobiologisch ungewöhnlichen Zeiten, kommt der Prävention von möglicherweise daraus resultierenden Erkrankungen und deren Folgen eine große Bedeutung zu. Aktuelle Erkenntnisse der Chronobiologie und der Arbeitsmedizin führen aber auch zu der Schlüsselfrage: Was wissen wir wirklich zum Zusammenhang von Schichtarbeit, Gesundheit und Krankheit?

 

  • Literatur

  • 1 EUROSTAT, Arbeitnehmer, die Schichtarbeit leisten, als Prozentsatz aller Arbeitnehmer, nach Geschlecht und Alter (%). 2014
    PubMedGoogle Scholar
  • 2 ArbZG, Arbeitszeitgesetz vom 6. Juni 1994 (BGBl. I S. 1170, 1171), das zuletzt durch Artikel 3 Absatz 6 des Gesetzes vom 20. April 2013 (BGBl. I S. 868) geändert worden ist. 1994/2013.
  • 3 Pittendrigh CS. Circadian rhythms and the circadian organization of living systems. Cold Spring Harb Symp Quant Biol 1960; 25: 159-184.
    CrossrefPubMedGoogle Scholar
  • 4 Pittendrigh CS. Temporal organization: reflections of a Darwinian clock-watcher. Annu Rev Physiol 1993; 55: 16-54.
    PubMedGoogle Scholar
  • 5 Ehret CF. The sense of time: evidence for its molecular basis in the eukaryotic gene-action system. Adv Biol Med Phys 1974; 15: 47-77.
    PubMedGoogle Scholar
  • 6 Toh KL. et al. An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. Science 2001; 291 (5506) 1040-1043.
    CrossrefPubMedGoogle Scholar
  • 7 Archer SN. et al. A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference. Sleep 2003; 26 (04) 413-415.
    CrossrefPubMedGoogle Scholar
  • 8 Dijk DJ, Duffy JF, Czeisler CA. Contribution of circadian physiology and sleep homeostasis to age-related changes in human sleep. Chronobiol Int 2000; 17 (03) 285-311.
    CrossrefPubMedGoogle Scholar
  • 9 Duffy JF, Czeisler CA. Age-related change in the relationship between circadian period, circadian phase, and diurnal preference in humans. Neurosci Lett 2002; 318 (03) 117-120.
    CrossrefPubMedGoogle Scholar
  • 10 Roenneberg T, Wirz-Justice A, Merrow M. Life between clocks: daily temporal patterns of human chronotypes. J Biol Rhythms 2003; 18 (01) 80-90.
    CrossrefPubMedGoogle Scholar
  • 11 Infante-Rivard C, Dumont M, Montplaisir J. Sleep disorder symptoms among nurses and nursing aides. Int Arch Occup Environ Health 1989; 61 (05) 353-358.
    CrossrefPubMedGoogle Scholar
  • 12 Hrushesky WJ. Circadian timing of cancer chemotherapy. Science 1985; 228 (4695) 73-75.
    CrossrefPubMedGoogle Scholar
  • 13 Kang TH. et al. Circadian oscillation of nucleotide excision repair in mammalian brain. Proc Natl Acad Sci U S A 2009; 106 (08) 2864-2867.
    CrossrefPubMedGoogle Scholar
  • 14 Foster RG, Wulff K. The rhythm of rest and excess. Nat Rev Neurosci 2005; 6 (05) 407-414.
    CrossrefPubMedGoogle Scholar
  • 15 Anonymous. Breakthrough of the year. The runners-up. Science 2002; 298 (5602) 2297-2303.
    PubMedGoogle Scholar
  • 16 Chen SK, Badea TC, Hattar S. Photoentrainment and pupillary light reflex are mediated by distinct populations of ipRGCs. Nature 2011; 476 (7358) 92-95.
    CrossrefPubMedGoogle Scholar
  • 17 Lucas RJ. et al. Measuring and using light in the melanopsin age. Trends Neurosci 2014; 37 (01) 1-9.
    CrossrefPubMedGoogle Scholar
  • 18 Foster R, Kreitzman L. The biological clocks that control the daily lives of every living thing: rhythms of life. London: Yale University Press profile books; 2004
    Google Scholar
  • 19 Erren TC, Reiter RJ, Piekarski C. Light, timing of biological rhythms, and chronodisruption in man. Naturwissenschaften 2003; 90 (11) 485-94.
    CrossrefPubMedGoogle Scholar
  • 20 Erren T. C. and R.J. Reiter, A generalized theory of carcinogenesis due to chronodisruption. Neuro Endocrinol Lett 2008; 29 (06) 815-821.
    PubMedGoogle Scholar
  • 21 Erren TC. et al. Shift work and cancer: the evidence and the challenge. Dtsch Arztebl Int 2010; 107 (38) 657-662.
    PubMedGoogle Scholar
  • 22 Straif K. et al. Carcinogenicity of shift-work, painting, and fire-fighting. Lancet Oncol 2007; 8 (12) 1065-1066.
    CrossrefPubMedGoogle Scholar
  • 23 IARC, IARC Monographs on the Evaluation of Carconogenic Risks to Humans. Volume 98 Painting, Fire-fighting, and Shiftwork; 2010
    Google Scholar
  • 24 Erren TC, Reiter RJ. Revisiting chronodisruption: when the physiological nexus between internal and external times splits in humans. Naturwissenschaften 2013; 100 (04) 291-298.
    CrossrefPubMedGoogle Scholar
  • 25 Erren TC, Reiter RJ. Defining chronodisruption. J Pineal Res 2009; 46 (03) 245-247.
    CrossrefPubMedGoogle Scholar
  • 26 Erren TC, Morfeld P. Computing chronodisruption: how to avoid potential chronobiological errors in epidemiological studies of shift work and cancer. Chronobiol Int 2014; 31 (04) 589-599.
    CrossrefPubMedGoogle Scholar
  • 27 Reiter RJ. et al. When the circadian clock becomes a ticking time bomb. Chronobiol Int 2012; 29 (09) 1286-1287.
    CrossrefPubMedGoogle Scholar
  • 28 Erren TC. Shift work, cancer and „white-box“ epidemiology: Association and causation. Epidemiol Perspect Innov 2010; 7: 11.
    CrossrefPubMedGoogle Scholar
  • 29 Erren TC. Shift work and cancer research: can chronotype predict susceptibility in night-shift and rotating-shift workers?. Occup Environ Med 2013; 70 (04) 283-284.
    CrossrefPubMedGoogle Scholar
  • 30 Juda M, Vetter C, Roenneberg T. The Munich ChronoType Questionnaire for Shift-Workers (MCTQShift). J Biol Rhythms 2013; 28 (02) 130-140.
    CrossrefPubMedGoogle Scholar
  • 31 Erren TC. et al. Chronodisruption and cancer. Naturwissenschaften 2008; 95 (05) 367-382.
    CrossrefPubMedGoogle Scholar
  • 32 Erren TC. et al. Shift work, chronodisruption and cancer? The IARC 2007 challenge for research and prevention and 10 theses from the Cologne Colloquium 2008. Scand J Work Environ Health 2009; 35 (01) 74-79.
    CrossrefPubMedGoogle Scholar
  • 33 Wicht H. et al. Chronotypes and rhythm stability in mice. Chronobiol Int 2014; 31 (01) 27-36.
    CrossrefPubMedGoogle Scholar