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Onkologische Welt 2010; 01(04): 167-168
DOI: 10.1055/s-0038-1632836
Neuro-Onkologie
Schattauer GmbH

Hirntumortherapie

Ein UpdateBrain tumour therapyAn update
H. Link
1   Medizinische Klinik I, Hämatologie und Onkologie, Westpfalz-Klinikum Kaiserslautern
,
R. Fink
2   Neurologische Klinik, Westpfalz-Klinikum Kaiserslautern
› Author Affiliations
Further Information

Publication History

Eingegangen am: 31 August 2009

angenommen am: 02 September 2009

Publication Date:
03 February 2018 (online)

Also available at
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Zusammenfassung

Die Therapie der primären Hirntumoren erfährt derzeit einen neuen Schub durch dia-gnostisch und therapeutisch relevante Erkenntnisse im molekularen Bereich. Es werden Defekte der Wachstumsregulation definiert, die in ähnlicher Form auch bei anderen malignen Erkrankungen vorkommen. Gegen diese definierten Defekte werden immer mehr zielgerichtete Therapien mit spezifischen Hemmstoffen verfügbar. Dadurch eröffnen sich neue Perspektiven, die Therapie zu verbessern.

Summary

Therapy of primary brain tumours gets a new impact by new insights into the molecular mechanisms of disturbed cell growth. It is possible, to define specific defects of cellular signal transduction cascades, which often use similar in other malignant tumours. Thus specific inhibitors available for other tumours may also be applied in gliomas providing new therapeutic options.

Schlüsselwörter

Gliome - Chemotherapie - molekulare Diagnostik - zielgerichtete Therapie

Keywords

Glioma - chemotherapy - molecular diagnostic - targeted therapy
 

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