Cortical Source Estimate of Combined High Resolution EEG and fMRI Data Related to Voluntary Movements

F. Babiloni; C. Babiloni; F. Carducci; Del C. Gratta; G. L. Romani; P. M. Rossini; F. Cincotti

doi:10.1055/s-0038-1634217

Methods of Information in Medicine, Table of Contents

Methods Inf Med 2002; 41(05): 443-450
DOI: 10.1055/s-0038-1634217

Original Article

Schattauer GmbH

Cortical Source Estimate of Combined High Resolution EEG and fMRI Data Related to Voluntary Movements

F. Babiloni

¹Dipartimento di Fisiologia Umana e Farmacologia, Università di Roma “La Sapienza”, Roma, Italy

,

C. Babiloni

¹Dipartimento di Fisiologia Umana e Farmacologia, Università di Roma “La Sapienza”, Roma, Italy

⁴AFaR and CRCCS Ospedale Fatebenefratelli, Isola Tiberina, Roma, Italy

,

F. Carducci

¹Dipartimento di Fisiologia Umana e Farmacologia, Università di Roma “La Sapienza”, Roma, Italy

⁴AFaR and CRCCS Ospedale Fatebenefratelli, Isola Tiberina, Roma, Italy

,

Del C. Gratta

²Dipartimento di Scienze Cliniche e Bioimmagini and Istituto di Tecnologie Avanzate Biomediche, Università “G. D’Annunzio”, Chieti, Italy

⁷Istituto Nazionale di Fisica della Materia, UdR L’Aquila, Italy

,

G. L. Romani

²Dipartimento di Scienze Cliniche e Bioimmagini and Istituto di Tecnologie Avanzate Biomediche, Università “G. D’Annunzio”, Chieti, Italy

⁷Istituto Nazionale di Fisica della Materia, UdR L’Aquila, Italy

,

P. M. Rossini

³IRCCS “San Giovanni di Dio”, Istituto Sacro Cuore di Gesù, Brescia, Italy

,

F. Cincotti

⁶IRCCS Fondazione Santa Lucia, Roma, Italy

› Author Affiliations

Abstract

Summary

Objectives: In this paper, we employed advanced methods for the modeling of human cortical activity related to voluntary right one-digit movements from combined high-resolution electroencephalography (EEG) and functional magnetic resonance imaging (fMRI).

Methods: Multimodal integration between EEG and fMRI data was performed by using realistic head models, a large number of scalp electrodes (128) and the estimation of current density strengths by linear inverse estimation.

Results: Increasing of spatial details of the estimated cortical density distributions has been detected by using the proposed integration method with respect to the estimation using EEG data alone.

Conclusion: The proposed method of multimodal EEG-fMRI data is useful to increase spatial resolution of movement-related potentials and can also be applied to other kinds of event-related potentials.

Keywords

High resolution EEG - fMRI - multimodal integration of EEG and fMRI - voluntary movements - event-related fMRI

Full Text

References

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