Periodical Multiphasic Screening and Lung Cancer Prevention

R. S. Carel

doi:10.1055/s-0038-1634518

Methods of Information in Medicine, Table of Contents

Methods Inf Med 1998; 37(02): 182-187
DOI: 10.1055/s-0038-1634518

Original Article

Schattauer GmbH

Periodical Multiphasic Screening and Lung Cancer Prevention

Authors

R. S. Carel

¹Dept of Occupational Medicine, Division of Community Health, Faculty of Health Sciences, Ben-Gurion University, Beer-Sheva, Israel and the MOR Institute for Medical Data, IsraeL

Abstract

The purpose of this work is to evaluate the utilization of information gathered by multiphasic screening with respect to lung cancer detection and smoking cessation techniques. A cohort (follow-up) study is reported in which cancer incidence and factors affecting its occurrence are evaluated in a group of about 20,000 presumably healthy adults along a period of approximately 10 years following comprehensive multiphasic health examinations. Lung cancer occurrence is primarily related to smoking. The risk is higher in smokers and is dose-dependent; OR = 0.21, (CI = 0.08,.53) in never smokers, OR = 1.53 (CI = 0.8,3.2) in past and current moderate smokers, OR = 4.92 (CI = 2.18,11.11) in current heavy smokers. Moreover, smokers with compromised pulmonary function (FEVI/FVC < 75%) are at an even higher risk of developing lung cancer OR = 4.22 (CI = 2.2, 8.2) for past and current moderate smokers; and OR = 10.7 (CI-2.5, 38.6) in current heavy smokers. Information gathered in periodical multiphasic health examinations could be utilized by health professionals to encourage smoking cessation and smoking prevention in the appropriate screenees. Various elements of the multiphasic test results could contribute to such prevention efforts. While every smoker should receive appropriate evaluation and consultation regarding nicotine dependence, smokers with reduced pulmonary function represent an extra high risk group to which special attention should be given.

Keywords

Multiphasic Screening - Lung Cancer - Smoking - Logistic Regression

Full Text

References

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