Thromb Haemost 1973; 30(01): 133-137
DOI: 10.1055/s-0038-1649109
Original Article
Schattauer GmbH

Fibrinoyltic Activity of Human Carcinomas

A Comparative Methodological Study
Hans-Inge Peterson
1   Departments of Surgery I, Oto-Rhino-Laryngology and Medicine II, Sahl-grenska Sjukhuset, University of Göteborg, Göteborg, Sweden
,
Björn Petrusson
1   Departments of Surgery I, Oto-Rhino-Laryngology and Medicine II, Sahl-grenska Sjukhuset, University of Göteborg, Göteborg, Sweden
,
Kristoffer Korsan-Bengtsen
1   Departments of Surgery I, Oto-Rhino-Laryngology and Medicine II, Sahl-grenska Sjukhuset, University of Göteborg, Göteborg, Sweden
› Author Affiliations
Further Information

Publication History

Received for publication 08 February 1973

Accepted for publication 08 June 1973

Publication Date:
30 June 2018 (online)

Summary

The fibrinolytic activity of 25 human malignant tumour specimens was studied by a semi-quantitative histochemical method and by a plasminogen activator extraction procedure. A good accordance between the results obtained with the two methods was found. The advantages and disadvantages of the methods are discussed.

 
  • References

  • 1 Astrup T, and Albrechtssen O. K. 1957; Estimation of the plasminogen activator and the trypsin inhibitor in animal and human tissues. Scandinavian Journal of Clinical and Laboratory Investigation 9: 233.
  • 2 Berg W, Korsan-Bengtsen K, and Ygge J. 1966; Human and bovine plasminogen-free thrombin purified by means of gel filtration and ion exchange chromatography. Thrombosis et Diathesis Haemorrhagica 15: 501.
  • 3 Bkakman P. 1967. Fibrinolysis, a standarized fibrin plate method and a fibrinolytic assay of plasminogen. Scheltema & Holkema; Amsterdam:
  • 4 Pandolfi M, Nilsson I. M, Robertson B, and Isacsson S. 1967; Fibrinolytic activity of human veins. Lancet 11: 127.
  • 5 Peterson H.-I. 1968 Experimental studies on fibrinolysis in growth and spread of tumour. Acta Chirurgica Scandinavica, Suppl. 394.
  • 6 Peterson H.-I, and Zettergren L. 1970; Thromboplastic and fibrinolytic properties of three transplantable rat tumours. Acta Chirurgica Scandinavica 136: 365.
  • 7 Peterson H.-I, Kjartansson L, Korsan-Bengtsen K, Rudenstam C.-M, and Zettergren L. 1973; Fibrinolysis in human malignant tumours. Acta Chirurgica Scandinavica 139: 219.
  • 8 Petrusson B. 1973 A micromethod for determination of tissue plasminogen activators in human mucosa. To be published.
  • 9 Todd A.S. 1958; Fibrinolysis autographs. Nature (London) 181: 495.
  • 10 Todd A. S. 1959; The histological localisation of fibrinolysin activator. Journal of Pathology and Bacteriology 78: 281.
  • 11 Rybo G. 1966 Plasminogen activators in the endometrium. Acta Obstetrica et Gynecologica Scandinavica. Suppl. 7.