Fibrinoyltic Activity of Human Carcinomas

Hans-Inge Peterson; Björn Petrusson; Kristoffer Korsan-Bengtsen

doi:10.1055/s-0038-1649109

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1973; 30(01): 133-137
DOI: 10.1055/s-0038-1649109

Original Article

Schattauer GmbH

Fibrinoyltic Activity of Human Carcinomas

A Comparative Methodological Study

Authors

Hans-Inge Peterson

¹Departments of Surgery I, Oto-Rhino-Laryngology and Medicine II, Sahl-grenska Sjukhuset, University of Göteborg, Göteborg, Sweden
Björn Petrusson

¹Departments of Surgery I, Oto-Rhino-Laryngology and Medicine II, Sahl-grenska Sjukhuset, University of Göteborg, Göteborg, Sweden
Kristoffer Korsan-Bengtsen

¹Departments of Surgery I, Oto-Rhino-Laryngology and Medicine II, Sahl-grenska Sjukhuset, University of Göteborg, Göteborg, Sweden

Abstract

Summary

The fibrinolytic activity of 25 human malignant tumour specimens was studied by a semi-quantitative histochemical method and by a plasminogen activator extraction procedure. A good accordance between the results obtained with the two methods was found. The advantages and disadvantages of the methods are discussed.

Full Text

References

References
1 Astrup T, and Albrechtssen O. K. 1957; Estimation of the plasminogen activator and the trypsin inhibitor in animal and human tissues. Scandinavian Journal of Clinical and Laboratory Investigation 9: 233.
2 Berg W, Korsan-Bengtsen K, and Ygge J. 1966; Human and bovine plasminogen-free thrombin purified by means of gel filtration and ion exchange chromatography. Thrombosis et Diathesis Haemorrhagica 15: 501.
3 Bkakman P. 1967. Fibrinolysis, a standarized fibrin plate method and a fibrinolytic assay of plasminogen. Scheltema & Holkema; Amsterdam:
4 Pandolfi M, Nilsson I. M, Robertson B, and Isacsson S. 1967; Fibrinolytic activity of human veins. Lancet 11: 127.
5 Peterson H.-I. 1968 Experimental studies on fibrinolysis in growth and spread of tumour. Acta Chirurgica Scandinavica, Suppl. 394.
6 Peterson H.-I, and Zettergren L. 1970; Thromboplastic and fibrinolytic properties of three transplantable rat tumours. Acta Chirurgica Scandinavica 136: 365.
7 Peterson H.-I, Kjartansson L, Korsan-Bengtsen K, Rudenstam C.-M, and Zettergren L. 1973; Fibrinolysis in human malignant tumours. Acta Chirurgica Scandinavica 139: 219.
8 Petrusson B. 1973 A micromethod for determination of tissue plasminogen activators in human mucosa. To be published.
9 Todd A.S. 1958; Fibrinolysis autographs. Nature (London) 181: 495.
10 Todd A. S. 1959; The histological localisation of fibrinolysin activator. Journal of Pathology and Bacteriology 78: 281.
11 Rybo G. 1966 Plasminogen activators in the endometrium. Acta Obstetrica et Gynecologica Scandinavica. Suppl. 7.