Summary
In vitro whole blood clots were incubated in SK, washed several times in Ringer-solution
and then introduced into plasminogen solution. These clots showed marked signs of
lysis surpassing those observed in clots that had only been incubated in SK. There
was a correlation between the duration of the SK incubation and the clot lysis in
the plasminogen solution. We deduce from these findings that SK enters the clots by
diffusion and that this process lasts several hours.
If SK-incubated clots are placed into an SK-free environment, the SK slowly diffuses
out of the thrombi.
Even in contact with very slight plasminogen concentrations, SK-incubated clots undergo
distinct degrees of lysis.
