The Venom of the Boomslang (Dispholidus Typus): In Vivo and in Vitro Studies

N Mackay; J.C Ferguson; Antonia Bagshawe; A.T.T Forrester; G.P Mcnicol

doi:10.1055/s-0038-1653532

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1969; 21(02): 234-244
DOI: 10.1055/s-0038-1653532

Originalarbeiten - Original Articles - Travaux Originaux

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The Venom of the Boomslang (Dispholidus Typus): In Vivo and in Vitro Studies

N Mackay M.B. (Glasg.), M.R.C.P. (Glasg., Edin.)^*¹⁾

¹Makerere University College Medical School Extension, Kenyatta National Hospital, Nairobi, and The Nairobi Snake Park

,

J.C Ferguson M.B. (Glasg.), M.R.C.P. (Glasg., Edin.)^*¹⁾

¹Makerere University College Medical School Extension, Kenyatta National Hospital, Nairobi, and The Nairobi Snake Park

,

Antonia Bagshawe M.B. (Lond.), M.R.C.P. (Lond., Edin.)

¹Makerere University College Medical School Extension, Kenyatta National Hospital, Nairobi, and The Nairobi Snake Park

,

A.T.T Forrester M.B. (Lond.), M.R.C.P. (Lond., Edin.)

¹Makerere University College Medical School Extension, Kenyatta National Hospital, Nairobi, and The Nairobi Snake Park

,

G.P Mcnicol M.D., Ph.D. (Glasg.), F.R.C.P. (Glasg., Edin.)^*²⁾

¹Makerere University College Medical School Extension, Kenyatta National Hospital, Nairobi, and The Nairobi Snake Park

› Author Affiliations

Abstract

Summary

An account is given of the effects of boomslang venom in man. Evidence was found of a fibrinolytic state apparently secondary to the coagulant action of the venom. These features rapidly responded to the administration of specific antivenom. In vitro studies, using a homogenate of boomslang parotids, confirmed the coagulant properties of the venom and showed them to be of much greater potency than the proteolytic actions.

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References

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