Download PDF
Thromb Haemost 1967; 17(03/04): 401-404
DOI: 10.1055/s-0038-1654163
Originalarbeiten - Original Articles - Travaux Originaux
Schattauer GmbH

Determination of Fibrinogen (and Fibrinolysis) in Small Quantities of Plasma

G Lázár M. D.
1   Institute of Pathophysiology (Director: Prof. Dr. S. Karády), Medical university, Szeged, Hungary
› Author Affiliations
Further Information

Publication History

Publication Date:
26 June 2018 (online)

Also available at
    Permissions and Reprints

Summary

The paper describes a simple method for the determination of fibrinogen and fibrinolysis especially suitable for serial examinations which may be performed with small amounts of plasma. In the procedures the amount of fibrin bound to the filter paper soaked in a thrombin solution is determined in the case of fibrinogen after washing, in that of fibrinolysis after incubation at 37° C and washing, by means of staining with fuchsine.

 

  • References

  • 1 Lózsa A. Papirelektroforesis készülék és methodika nagy számu szérumminta fehérje-fractióinak szeparálására és festésére. Kisérl. Orvostud 13: 86-97 1961;
    PubMedSearch in Google Scholar
  • 2 Burdon K. L, McGoverns J. P, Barkin G. D, Meyers W. M. Fibrinolysis and anaphylaxis. I. Activation of blood fibrinolysin during acute anaphylactic shock in guinea pigs. J. Allergy 52: 55-62 1961;
    PubMedSearch in Google Scholar
  • 3 Horányi M. Ein neues Verfahren zur Hemmung der Blutgerinnung bei der Gravimetrischen Bestimmung desnativen Fibrinogens. Klin. Wschr 20: 1128-1129 1941;
    CrossrefPubMedSearch in Google Scholar
  • 4 Gerendás M. Véralvadás és vérzéscsillapitás. Medicina; Budapest: 1960
    Search in Google Scholar
  • 5 Reiner M, Cheung H. L. A practical method for the determination of fibrinogen. Clin. Chem 5: 414-420 1959;
    PubMedSearch in Google Scholar
  • 6 Ratnoff O. D, Menzie C. A new method for the determination of fibrinogen in small samples of plasma. J. Lab. clin. Med 37: 316-320 1951;
    PubMedSearch in Google Scholar
  • 7 Parfentjev I. A, Johson M. L, Cliffton E. E. The determination of plasma fibrinogen by turbidity with ammonium sulfate. Arch. Biochem 46: 470-480 1953;
    CrossrefPubMedSearch in Google Scholar
  • 8 Clauss A. Gerinnungsphysiologische Schnellmethode zur Bestimmung des Fibrinogens. Acta haemat. (Basel) 17: 237-246 1957;
    CrossrefPubMedSearch in Google Scholar
  • 9 Schneider Ch. L. Rapid estimation of plasma fibrinogen concentration and its use as a guide to therapy of intravascular defibrination. Amer. J. Obstet. Gynec 64: 141-147 1952;
    CrossrefPubMedSearch in Google Scholar
  • 10 Dóczy Á, Gerendás M, Hollcm Zs. A vèr fibrinogen tartalmának gyors meghatározása. Haemat. hung 2: 101-106 1962;
    PubMedSearch in Google Scholar
  • 11 Horányi M. Fibrinopenia és sulyos vérzékenység csontvelö carcinosisban. Orv. Hetil 92: 1077-1078 1951;
    PubMedSearch in Google Scholar