Some Properties of an Antiplasmin Substance from Rabbit Platelets

K Wakabayashi; K Fujikawa; T Abe

doi:10.1055/s-0038-1654213

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1970; 24(01/02): 076-084
DOI: 10.1055/s-0038-1654213

Originalarbeiten – Original Articles – Travaux Originaux

Schattauer GmbH

Some Properties of an Antiplasmin Substance from Rabbit Platelets

K Wakabayashi

¹Tokyo University School of Medicine, Tokyo; First Department of Surgery and First Department of Medicine, Institute for Protein Research, Osaka University, Osaka

,

K Fujikawa

¹Tokyo University School of Medicine, Tokyo; First Department of Surgery and First Department of Medicine, Institute for Protein Research, Osaka University, Osaka

,

T Abe

¹Tokyo University School of Medicine, Tokyo; First Department of Surgery and First Department of Medicine, Institute for Protein Research, Osaka University, Osaka

› Author Affiliations

Abstract

Summary

Rabbit platelets contained a proteinase inhibitor which inhibited plasmin, trypsin and chymotrypsin activities, and serum kallikrein to some extent. It did not inhibit pancreatic kallikrein and thrombin. It reacted stoechiometrically with these enzymes in a prompt fashion and was found to have a molecular weight of about 40,000.

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References

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