Additional Evidence for the Existence of a Precursor Molecule of the Prothrombin Complex in Oral Anticoagulation

Summary

By means of the PTC-inhibitor neutralizing test (12) a significant excess of PTC (factor IX)-like material over factor IX activity could be demonstrated in human coumarin plasma. This cross-reacting material is considered to be a precursor of one or all of the clotting factors of the prothrombin complex.

• References

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