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Thromb Haemost 1963; 10(01): 146-150
DOI: 10.1055/s-0038-1654770
Originalarbeiten — Original Article — Travaux Originaux
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The Effect of Aminopterin Sodium on Plasma Fibrinogen, Antifibrinolysin and Euglobulin Lysis Time[*]

J Frederic Johnson
1   Department of Physiology and Pharmacology, Wayne State University College of Medicine, Detroit, Michigan, USA
,
Rashid A Zeineh
1   Department of Physiology and Pharmacology, Wayne State University College of Medicine, Detroit, Michigan, USA
› Author Affiliations
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Publication Date:
22 June 2018 (online)

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Summary

The daily oral administration of Aminopterin Sodium to normal dogs was accompanied by an increase in plasma antifibrinolysin concentration, an increase in plasma fibrinogen concentration and a decrease in euglobulin fibrinolytic activity.

* This investigation was supported by a research grant HE-05141 from the National Heart Institute, National Institute of Health, U.S. Public Health Service.


 

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