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Thromb Haemost 1961; 05(03): 489-494
DOI: 10.1055/s-0038-1654942
Originalarbeiten – Original Article – Travaux Originaux
Schattauer GmbH

The Standard Clot[*]

with the technical assistance of Charles Taylor
Kurt N. von Kaulla
1   Department of Medicine, University of Colorado School of Medicine and Belle Bonfils Memorial Blood Bank, Denver
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Publication History

Publication Date:
21 June 2018 (online)

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Summary

A method has been developed which allows fibrinolytic materials to be tested under standardized conditions on preformed plasma or fibrin clots. The clot is digested from one unvaried surface only. The progress of the digestion can be read directly as volume of clot digested as often as desired. The method is particularly suitable for serial studies with preformed clots from human plasma.

* Supported by grants-in-aid from the American Heart Association, Inc. and the Belle Bonfils Memorial Blood Bank.


 

  • References

  • 1 Astrup T, Muellertz S. The fibrin plate method for estimating fibrinolytic activity. Arch. Biochem. Biophys 40: 346 1952;
    CrossrefPubMedSearch in Google Scholar
  • 2 von Kaulla K. N. Methods for preparation of purified human thromboplastin and fibrinolysokinase from urine. Acta haemat. (Basel) 16: 316 1956;
    PubMedSearch in Google Scholar
  • 3 von Kaulla K. N. Urokinase-induced fibrinolysis of human standard clots. Nature (Lond). 184. 1320 1959 — Die Rolle des Aktivators beim Abbau menschlicher Fibringerinnsel. Klin. Wschr. 38: 288 (1960). — Fibrinolysis in man induced by non-enzymatic non-pyrogenic drugs. Conference on Thrombolytic Agents, p. 94—106. Chicago 1960..
    PubMedSearch in Google Scholar