Thrombosis and Haemostasis, Inhaltsverzeichnis Thromb Haemost 1963; 09(01): 090-101DOI: 10.1055/s-0038-1654963 Originalarbeiten — Original Articles — Travaux Originaux Schattauer GmbH The Relation of Factors XII, XI, and IX to Hypercoagulable States[*] [**] With the technical assistance of Jacqueline D. La Croix and V. Jane Cranney Duncan P Thomas 1 Medical Research Department of the Yamins Research Laboratory, Beth Israel Hospital, and the Department of Medicine, Harvard Medical School , Stanford Wessler 1 Medical Research Department of the Yamins Research Laboratory, Beth Israel Hospital, and the Department of Medicine, Harvard Medical School , Stanley M Reimer 1 Medical Research Department of the Yamins Research Laboratory, Beth Israel Hospital, and the Department of Medicine, Harvard Medical School › Institutsangaben Artikel empfehlen Abstract Artikel einzeln kaufen Summary Evidence has been obtained in rabbits that the reduction of the silicone whole blood clotting time to the normal glass range reflects a hypercoagulable state attributable to circulating activated factors XII and XI. The potential clinical implications of these findings are discussed. Volltext Referenzen References 1 Wessler S. Studies in intravascular coagulation. III. The pathogenesis of seruminduced venous thrombosis. J. clin. Invest. 34: 647 1955; 2 Wessler S, Reimer S. M. The role of human coagulation factors in serum-induced thrombosis. J. clin. Invest. 39: 262 1960; 3 Reimer S. M, Wessler S, Deykin D. Serum thrombotic accelerator (STA) activity: its relation to the first phase of clotting. Proc. Soc. exp. Biol. (N. Y) 105: 438 1960; 4 Wessler S, Freiman D. G, Suyemoto J, Reimer S. M. Serum thrombotic accelerator (STA) activity: a possible key to massive venous thromboembolism in man. Trans. Ass. Amer. Phys. 74: 111 1961; 5 Henderson E. S, Rapaport S. I. Evidence that Activation Product causes serum-induced thrombosis. Clin. Res. 09: 160 1961; 6 Didisheim P, Vandervoort R. L. E, Rytting J. E. Formation of serum thrombotic accelerator (STA) in plasma. Clin. Res. 10: 77 1962; 7 Wessler S, Reiner L, Freiman D. G, Reimer S. M, Lertzman M. Serum-induced thrombosis: Studies of its induction and evolution under controlled conditions in vivo. Circulation 20: 864 1959; 8 Rees H. M, Ecker E. E. An improved method for counting blood platelets. J. Amer. med. Ass. 80: 621 1923; 9 Ware A. G, Seegers W. H. Two-stage procedure for the quantitative determination of prothrombin concentration. Amer. J. clin. Path. 19: 471 1949; 10 Wessler S, Reimer S. M, Sheps M. C. Biologie assay of a thrombosisinducing activity in human serum. J. appl. Physiol. 14: 943 1959; 11 Lee R. I, White P. D. A clinical study of the coagulation time of blood. Amer. J. med. Sci. 145: 495 1913; 12 Waaler B. A. Contact activation in the intrinsic blood clotting system. Scand. J. clin. Lab. Invest. (Suppl) 11: 37 1959; 13 Wartelle O. Les facteurs prothromboplastiques du sang de poule et de quelques mammifères. Thèse, Travail du Centre National de Transfusion, Sanguine, Paris 1959 14 Thompson J. H, Spittel J. A, Pascuzzi C. A, Owen C. A. Laboratory and genetic observations in another family with the Hageman trait. Proc. Mayo Clin. 35: 421 1960; 15 Fanti P. A comparative study of blood coagulation in vertebrates. Aust. J. exp. Biol, med. Sci. 39: 404 1961; 16 Soulier J. P. Our present knowledge of PTA factor. Thrombos. Diathes. haemorrh. Suppl. ad IV: 123 1960; 17 Henderson E. S, Rapaport S. The thrombotic activity of activation product. J. clin. Invest. 41: 235 1962; 18 Ratnoff O. D, Davie E. W, Mallett D. L. Studies on the action of Hageman factor: Evidence that activated Hageman factor in turn activates plasma thromboplastin antecedent. J. clin. Invest. 40: 803 1961; 19 Ratnoff O. D. The activation of Christmas factor by activated plasma thromboplastin antecedent. J. clin. Invest. 40: 1074 1961; 20 Ferguson J. H, Wilson E. G, Iatridis S. G, Rierson H. A, Johnston B. R. Enzymes and blood clotting. I. Trypsin as an accessory factor. J. clin. Invest. 39: 1942 1960; 21 Wessler S, Cohen S, Fleischner F. G. The temporary thrombotic state. Application of this concept to the therapy of recurrent thromboembolism, with bactériologie and roentgenologic considerations in the differential diagnosis of pulmonary infarction and pneumonia. New Engl. J. Med. 254: 413 1956; 22 Tillett W. S, Johnson A. Personal communication.
