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J Pediatr Intensive Care 2019; 08(02): 071-077
DOI: 10.1055/s-0038-1667380
Original Article
Georg Thieme Verlag KG Stuttgart · New York

Practice Patterns after the Therapeutic Hypothermia After Pediatric Cardiac Arrest Out-of-Hospital Trial: A Survey of Pediatric Critical Care Physicians

Marianne R. Gildea
1   Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States
,
Frank W. Moler
2   Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, United States
,
Kent Page
1   Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States
,
Victoria L. Pemberton
3   National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States
,
Richard Holubkov
1   Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States
,
Vinay M. Nadkarni
4   Department of Anesthesiology and Critical Care Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States
,
J. Michael Dean
1   Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States
,
Lenora M. Olson
1   Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States
› Author Affiliations
Further Information

Publication History

02 April 2018

24 June 2018

Publication Date:
12 August 2018 (online)

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Abstract

The Therapeutic Hypothermia After Pediatric Cardiac Arrest Out-of-Hospital (THAPCA-OH) Trial showed therapeutic hypothermia, versus normothermia, did not significantly improve 1-year survival with good neurobehavioral outcome. Our survey of pediatric critical care physicians, designed to assess the use of targeted temperature management (TTM) after publication of the main THAPCA-OH Trial results, found most respondents were aware of trial results, and over 90% agreed THAPCA-OH was well-designed with important clinical outcomes. While most respondents reported TTM usage consistent with THAPCA-OH results in different patient scenarios, 15% did not select TTM for fever management. Since trials prior to THAPCA-OH established that fever is harmful following brain injury, the continued incomplete adoption of TTM warrants further research on challenges and facilitators to the adoption of clinical trial findings.

Keywords

targeted temperature management - THAPCA-OH - survey

Supplementary Material

 

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