The Impact of Pharmaceutical Side Effects on Audiological and Vestibular Measurements

Robert M. DiSogra

doi:10.1055/s-0039-1684039

Seminars in Hearing, Table of Contents

Semin Hear 2019; 40(02): 097-103
DOI: 10.1055/s-0039-1684039

Review Article

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

The Impact of Pharmaceutical Side Effects on Audiological and Vestibular Measurements

Robert M. DiSogra

¹School of Communication Disorders and Deafness, Kean University, Union, New Jersey

› Author Affiliations

Abstract

There are over 2,000 drugs with a combined total of over 400 side effects that could result in obtaining inaccurate case history information or inaccurate test results that may lead to misdiagnosing the patient's hearing or vestibular problem. The recommendations that are made could be inappropriate and thus can lead to management errors. A review of the auditory, vestibular, and cognitive side effects of many of the drugs patients take regularly (including drugs that can cause tinnitus) is provided. This article offers suggestions to obtain a more accurate case history. A review of preferred Web sites to obtain drug side effect information is included. Suggestions for improved communication strategies between the audiologist, the physician, the patient, and the pharmacist are highlighted.

Keywords

adverse drug reaction - case history - ototoxicity - vestibular problem

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References

References
1 DiSogra RM. Adverse drug reactions and audiology practice. Audiol Today, September 2008
2 U.S. Food and Drug Administration. Available at: www.fda.gov/ForPatients/Approvals/Drugs/default.htm . Accessed February 28, 2019
3 DiMasi JA, Grabowski HG, Hansen RW. Innovation in the pharmaceutical industry: new estimates of R&D costs. Boston, MA: Tufts Center for the Study of Drug Development; November 18, 2014
4 Tufts Center for the Study of Drug Development. Available at: http://csdd.tufts.edu/news/complete_story/cost_study_press_event_webcast . Accessed February 28, 2019
5 Winker MA, Flanagin A, Chi-Lum B. , et al; American Medical Association. Guidelines for medical and health information sites on the internet: principles governing AMA web sites. JAMA 2000; 283 (12) 1600-1606
6 Qato DM, Wilder J, Schumm LP, Gillet V, Alexander GC. Changes in prescription and over-the-counter medication and dietary supplement use among older adults in the United States, 2005 vs 2011. JAMA Intern Med 2016; 176: 47
7 Centers for Disease Control and Prevention. 2016 . Available at: http://www.cdc.gov . Accessed March 1, 2019
8 Rscin JM, Linnebur SA. Drug-related problems in the elderly. 2014 . Available at: http://www.merckmanuals.com/professional/geriatrics/drug-therapy-in-the-elderly/drug-related-problems-in-the-elderly . Accessed March 1, 2019
9 SIDER 2. 2018 . Available at: http://sideeffects.embl.de . Accessed March 1, 2019
10 Bushardt RL, Massey EB, Simpson TW, Ariail JC, Simpson KN. Polypharmacy: misleading, but manageable. Clin Interv Aging 2008; 3 (02) 383-389
11 Humes LE. Speech understanding in the elderly. J Am Acad Audiol 1996; 7 (03) 161-167
12 Sweetow R. Unique needs of elderly hearing impaired patients. Paper presented at the annual meeting of the American Academy of Audiology, 2013
13 Kennedy B. , ed. PDR guide to drug interactions, side effects, and indications, 64th ed. Montvale, NJ: PDR Network, LLC; 2009
14 Rochon PA. Drug prescribing for older adults. 2016 . Available at: http://www.uptodate.com . Accessed March 1, 2019
15 DiSogra RM. Ototoxicity: tinnitus as a drug side effect. Tinnitus Today, July 2018