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Thromb Haemost 2019; 119(07): 1058-1071
DOI: 10.1055/s-0039-1687876
Coagulation and Fibrinolysis
Georg Thieme Verlag KG Stuttgart · New York

Cholesterol Starvation and Hypoxia Activate the FVII Gene via the SREBP1-GILZ Pathway in Ovarian Cancer Cells to Produce Procoagulant Microvesicles

Shiro Koizume
1   Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan
,
Tomoko Takahashi
1   Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan
,
Mitsuyo Yoshihara
1   Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan
,
Yoshiyasu Nakamura
1   Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan
,
Wolfram Ruf
2   Center for Thrombosis and Hemostasis, Johannes Gutenberg University Medical Center, Mainz, Germany
3   Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States
,
Katsuya Takenaka
1   Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan
,
Etsuko Miyagi
4   Department of Obstetrics, Gynecology, and Molecular Reproductive Science, Graduate School of Medicine, Yokohama City University, Yokohama, Japan
,
Yohei Miyagi
1   Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan
› Author Affiliations