Synthesis, Table of Contents Synthesis 2020; 52(12): 1833-1840DOI: 10.1055/s-0039-1691740 paper © Georg Thieme Verlag Stuttgart · New York Synthesis of 2,4-Diarylquinoline Derivatives via Chloranil-Promoted Oxidative Annulation and One-Pot Reaction Dongping Cheng∗ a College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. of China , Xianhang Yan a College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. of China , Jing Shen a College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. of China , Yueqi Pu a College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. of China , Xiaoliang Xu∗ b College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, P. R. of China Email: chengdp@zjut.edu.cn , Jizhong Yan∗ a College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. of China › Author Affiliations Recommend Article Abstract Buy Article All articles of this category Abstract An oxidative annulation for the synthesis of 2,4-diarylquinolines from o-allylanilines is disclosed that uses recyclable reagent Chloranil as the oxidant. The corresponding products are obtained in moderate to excellent yields. Furthermore, a one-pot access to 2,4-diarylquinolines from easily available anilines and 1,3-diarylpropenes is described as a highly atom-efficient protocol that involves oxidative coupling, rearrangement, and oxidative annulation. Key words Key wordsoxidative annulation - one-pot reaction - chloranil - 2,4-diarylqunoline Full Text References References 1 Chen YL, Fang KC, Sheu JY, Hsu SL, Tzeng CC. J. Med. Chem. 2001; 44: 2374 2 Kaur K, Jain M, Reddy RP, Jain R. Eur. J. Med. Chem. 2010; 45: 3245 3 Praveen C, DheenKumar P, Muralidharan D, Perumal PT. Bioorg. Med. Chem. Lett. 2010; 20: 7292 4 Mukherjee S, Pal M. 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