CsF-Catalyzed Fluoroacylation of Tetrafluoroethylene Using Acyl Fluorides for the Synthesis of Pentafluoroethyl Ketones

Abstract

A catalytic method for the synthesis of pentafluoroethyl ketones­ has been developed. The cesium fluoride catalyst can be used to convert acyl fluorides into the pentafluoroethyl ketones under tetrafluoroethylene pressure without generating stoichiometric quantities of chemical waste. Mechanistic studies suggest that high reaction temperature is crucial for the ketone to be the major product.

Key words

acyl fluoride - tetrafluoroethylene - pentafluoroethyl ketone­ - pentafluoroethylation - cesium fluoride - DFT calculations

Publication History

Received: 08 September 2020

Accepted after revision: 30 September 2020

Article published online:
28 October 2020

• References

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