Synthesis, Table of Contents Synthesis 2021; 53(07): 1372-1378DOI: 10.1055/s-0040-1705973 paper 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ)-Mediated Tandem Oxidative-Coupling/Annulation of o-Hydroxyaryl Enaminones with Cycloheptatriene Dongping Cheng∗ a College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. China Email: chengdp@zjut.edu.cn , Yueqi Pu a College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. China Email: chengdp@zjut.edu.cn , Mingliang Wang a College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. China Email: chengdp@zjut.edu.cn , Yinqiang Shen a College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. China Email: chengdp@zjut.edu.cn , Jing Shen a College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. China Email: chengdp@zjut.edu.cn , Xiaoliang Xu∗ b College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, P. R. China , Jizhong Yan a College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. China Email: chengdp@zjut.edu.cn › Author Affiliations Recommend Article Abstract Buy Article All articles of this category Abstract A DDQ-mediated tandem reaction of easily available o-hydroxyaryl enaminones and cycloheptatriene is disclosed. It provides an effective and convenient method for the synthesis of 3-(cycloheptatrienyl)-substituted chromones in moderate to excellent yields with good functional group tolerance; this reaction involves an oxidative coupling and intramolecular annulation pathway. Key words Key wordsannulation - alkylation - DDQ - o-hydroxyaryl enaminones - cycloheptatriene Full Text References References 1a Khan KM, Ambreen N, Mughal UR, Jalil S, Perveen S, Choudhary MI. Eur. J. Med. 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