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Synlett 2020; 31(18): 1823-1827
DOI: 10.1055/s-0040-1707258
letter

Utility of N-Bromosuccinimide–Water Combination as a Green Reagent for Synthesis of N,S-Heterocycles and Dithiocarbamates from Styrenes

Firouz Matloubi Moghaddam  ∗
Laboratory of Organic Synthesis and Natural Products, Department of Chemistry, Sharif University of Technology, Azadi Street, P.O. Box 111559516, Tehran, Iran
,
Mehri Goudarzi
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Abstract

An efficient and unprecedented green protocol has been developed for the synthesis of N,S-heterocycles from styrenes and alkyl dithiocarbamates with high to excellent yields. The reaction of primary or secondary amines, CS2, and styrenes was carried out in water in the presence of a catalytic amount of an inorganic base. All products were made by using an N-bromosuccinimide–H2O combination as a green and inexpensive reagent.

Key words

dithiocarbamates - styrenes - green chemistry - thiazoles - bromosuccinimide

Supporting Information

    Supporting information for this article is available online at https://doi.org/10.1055/s-0040-1707258.
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Publication History

Received: 22 May 2020

Accepted after revision: 10 July 2020

Article published online:
28 August 2020

© 2020. Thieme. All rights reserved

Georg Thieme Verlag KG
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