Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000083.xml
Synlett 2020; 31(15): 1517-1522
DOI: 10.1055/s-0040-1707891
DOI: 10.1055/s-0040-1707891
letter
Silver-Catalyzed Decarboxylative Radical Addition/Cyclization of Oxamic Acids with Alkenes towards Quinolin-2-ones
Financial support from the National Natural Science Foundation of China (21302130 and 21676166), the Science and Technology Department of Zhejiang Province (2014C31141 and LGG20B060002), and the Department of Education of Zhejiang Province (Y201941045) are acknowledged with thanks.Further Information
Publication History
Received: 16 April 2020
Accepted after revision: 21 May 2020
Publication Date:
21 July 2020 (online)


Abstract
An efficient silver-catalyzed tandem decarboxylative radical addition/cyclization of oxamic acids with alkenes has been developed. This method provides a novel and straightforward protocol toward a variety of 4-aryl-3,4-dihydroquinolin-2(1H)-ones, 4-(α-carbonyl)-3,4-dihydroquinolin-2(1H)-ones, and quinolin-2(1H)-ones in aqueous solution.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0040-1707891.
- Supporting Information