Synthesis 2020; 52(20): 3001-3006
DOI: 10.1055/s-0040-1707899
paper
© Georg Thieme Verlag Stuttgart · New York

An Efficient Copper-Catalyzed C(sp2)–S Formation Starting from Aryl Iodides and Tetramethylthiuram Monosulfide (TMTM)

Yue-Xiao Wu
a   School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan 430205, P. R. of China
,
Kang Peng
a   School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan 430205, P. R. of China
,
Jing-Hang Li
a   School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan 430205, P. R. of China
,
Zhi-Bing Dong
a   School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan 430205, P. R. of China
b   Key Laboratory of Green Chemical Process, Ministry of Education, Wuhan Institute of Technology, Wuhan 430205, P. R. of China
c   Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, Hubei University, Wuhan 430062, P. R. of China
d   Hubei Key Laboratory of Novel Reactor and Green Chemistry Technology, Wuhan Institute of Technology, Wuhan 430205, P. R. of China   Email: dzb04982@wit.edu.cn
› Author Affiliations
Financial support from Hubei Key Laboratory of Radiation Chemistry and Functional Materials, Hubei University of Science & Technology (2019-20KZ01), Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, Hubei University (KLSAOFM1810), Science and Technology Department of Hubei Province­ (2019CFB596), Key Laboratory of Hubei Province for Coal Conversion and New Carbon Materials (WKDM202003) are greatly appreciated.
Further Information

Publication History

Received: 22 April 2020

Accepted after revision: 01 June 2020

Publication Date:
20 July 2020 (online)


Abstract

A new, efficient copper-catalyzed C(sp2)–S formation of phenyl dithiocarbamates starting from aryl iodides and tetramethylthiuram monosulfide (TMTM) was developed. The target compounds, phenyl dithiocarbamates with active sites, were synthesized smoothly in good to excellent yields. The easy performance, high yields, decent functional group compatibility, and cost-effective substrates make the protocol practical and attractive in C–S bond formation.

Supporting Information