American Journal of Perinatology, Inhaltsverzeichnis

Am J Perinatol 2021; 38(13): 1386-1392
DOI: 10.1055/s-0040-1712967

Original Article

Quality Improvement Efforts Reduce Incidence of Surgical Necrotizing Enterocolitis and Related Deaths

Gillian R. Goddard

¹Division of Pediatric and General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

,

²Department of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, Ohio

³Division of Neonatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

,

Anne Poindexter

¹Division of Pediatric and General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

²Department of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, Ohio

,

Todd Jenkins

¹Division of Pediatric and General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

²Department of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, Ohio

,

Jacqueline Wessel

¹Division of Pediatric and General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

,

Amy T. Nathan

²Department of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, Ohio

³Division of Neonatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

,

Michael A. Helmrath

¹Division of Pediatric and General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

²Department of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, Ohio

,

Brenda Poindexter

²Department of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, Ohio

³Division of Neonatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

› Institutsangaben

Abstract

Objective The aim of this study was to determine whether a regional quality improvement (QI) initiative decreased incidence and severity of surgical necrotizing enterocolitis (NEC) in very low birth weight (VLBW) infants.

Study Design A retrospective review of all VLBW infants who received care at one of the three hospitals involved in a NEC QI initiative from 2011 to 2016. Primary outcome was the number of surgical NEC cases per year. Secondary outcomes included associated outcomes and mortality.

Results Sixty-three infants with either a diagnosis of Stage III NEC (n = 40) or spontaneous intestinal perforation (SIP) (n = 23) were included. The incidence of medical and surgical NEC and the mortality rate of infants with surgical NEC decreased over time. Incidence and mortality of SIP did not significantly change.

Conclusion A regional QI bundle to reduce the overall incidence of NEC also significantly decreased the incidence of surgical NEC and all-cause mortality of infants diagnosed with surgical NEC.

Key Points

QI reduces surgical necrotizing enterocolitis.
Reduction in NEC rate improves mortality.
Human milk does not change SIP incidence.

Keywords

Keywords

necrotizing enterocolitis - prematurity - quality improvement - very low birth weight

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