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Semin intervent Radiol 2020; 37(03): 285-294
DOI: 10.1055/s-0040-1713446
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

The Role of Interventional Radiologists in the Treatment of Congenital Lymphatic Malformations

Julie Cronan
1   Division of Interventional Radiology and Image-Guided Medicine, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia
,
Anne E. Gill
1   Division of Interventional Radiology and Image-Guided Medicine, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia
2   Division of Pediatric Radiology, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia
,
Jay H. Shah
1   Division of Interventional Radiology and Image-Guided Medicine, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia
2   Division of Pediatric Radiology, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia
,
C. Matthew Hawkins
1   Division of Interventional Radiology and Image-Guided Medicine, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia
2   Division of Pediatric Radiology, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia
› Author Affiliations
Further Information

Publication History

Publication Date:
31 July 2020 (online)

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Abstract

Lymphatic malformations are low-flow vascular malformations that are typically apparent in the pediatric population and can cause significant functional limitations and effects on quality of life. While surgical resection has historically been the mainstay of therapy, percutaneous sclerotherapy has garnered increasing popularity due to its efficacy and low complication rates. The role of interventional radiology in the multidisciplinary management of these often complex malformations requires thorough understanding of the disease process. This article will review the pathophysiology, clinical presentation, imaging workup, and management options of lymphatic malformations. Special attention will be devoted to available sclerosants, the mammalian target of rapamycin inhibitor sirolimus, and complex lymphatic anomalies.

Keywords

lymphatic malformation - sclerotherapy - sirolimus

Notes

No funding was received for this study. The data have not been submitted for presentation at any meeting.


 

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