Holmium-166 Radioembolization

Abstract

Radioembolization is usually performed with microspheres containing yttrium-90 (⁹⁰Y). Holmium-166 (¹⁶⁶Ho)-microspheres were developed as an alternative new product for radioembolization. The unique characteristics of ¹⁶⁶Ho-microspheres allow for improved imaging possibilities. They can be visualized and quantified, already at low numbers and activities, to predict treatment distribution using ¹⁶⁶Ho-microspheres at scout quantity during pre-treatment simulation. The option to reliably predict the distribution of microspheres provides physicians control over the treatment, allowing them to select and treat patients with a personalized treatment plan. Safety and efficacy were established in several clinical studies. ¹⁶⁶Ho-microspheres radioembolization aims to optimize individualized treatment planning in order to improve treatment outcomes.

Keywords

radioembolization - holmium - liver

Publication History

Received: 03 December 2020

Accepted: 22 December 2020

Article published online:
15 April 2021

• References

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