Muscular Oxygen Uptake Kinetics in Aged Adults

J. Koschate; U. Drescher; K. Baum; S. Eichberg; T. Schiffer; J. Latsch; K. Brixius; U. Hoffmann

doi:10.1055/s-0042-101413

International Journal of Sports Medicine, Table of Contents

Int J Sports Med 2016; 37(07): 516-524
DOI: 10.1055/s-0042-101413

Physiology & Biochemistry

Muscular Oxygen Uptake Kinetics in Aged Adults

J. Koschate

¹Institute of Physiology and Anatomy, German Sport University Cologne, Cologne, Germany

,

U. Drescher

¹Institute of Physiology and Anatomy, German Sport University Cologne, Cologne, Germany

,

K. Baum

¹Institute of Physiology and Anatomy, German Sport University Cologne, Cologne, Germany

,

S. Eichberg

²Institute of Sport Gerontology, Cologne, German Sport University Cologne, Cologne, Germany

,

T. Schiffer

³Outpatient Clinic for Sports Traumatology and Public Health Consultation, German Sport University Cologne, Cologne, Germany

,

J. Latsch

⁴Institute of Cardiovascular Research and Sports Medicine, Department of Preventive and Rehabilitative Sport Medicine, German Sport University Cologne, Cologne, Germany

,

K. Brixius

⁵Institute of Cardiovascular Research and Sport Medicine, Department of Molecular and Cellular Sport Medicine, Cologne, Germany

,

U. Hoffmann

¹Institute of Physiology and Anatomy, German Sport University Cologne, Cologne, Germany

› Author Affiliations

Abstract

Pulmonary oxygen uptake (V˙O₂) kinetics and heart rate kinetics are influenced by age and fitness. Muscular V˙O₂ kinetics can be estimated from heart rate and pulmonary V˙O₂. In this study the applicability of a test using pseudo-random binary sequences in combination with a model to estimate muscular V˙O₂ kinetics was tested. Muscular V˙O₂ kinetics were expected to be faster than pulmonary V˙O₂ kinetics, slowed in aged subjects and correlated with maximum V˙O₂ and heart rate kinetics. 27 elderly subjects (73±3 years; 81.1±8.2 kg; 175±4.7 cm) participated. Cardiorespiratory kinetics were assessed using the maximum of cross-correlation functions, higher maxima implying faster kinetics. Muscular V˙O₂ kinetics were faster than pulmonary V˙O₂ kinetics (0.31±0.1 vs. 0.29±0.1 s; p=0.004). Heart rate kinetics were not correlated with muscular or pulmonary V˙O₂ kinetics or maximum V˙O₂. Muscular V˙O₂ kinetics correlated with maximum V˙O₂ (r=0.35; p=0.033). This suggests, that muscular V˙O₂ kinetics are faster than estimates from pulmonary V˙O₂ and related to maximum V˙O₂ in aged subjects. In the future this experimental approach may help to characterize alterations in muscular V˙O₂ under various conditions independent of motivation and maximal effort.

Key word

exercise capacity - pseudo-random binary sequences - cardiorespiratory kinetics

Full Text

References

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