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Dtsch Med Wochenschr 2017; 142(02): 88-95
DOI: 10.1055/s-0042-105942
DOI: 10.1055/s-0042-105942
Dossier
Extrakorporale Lungenunterstützung bei Patienten mit ARDS
Extracorporeal Lung Support in Patients with ARDSFurther Information
Publication History
Publication Date:
23 January 2017 (online)
Das akute Lungenversagen (ARDS) ist gekennzeichnet durch eine schwere Gasaustauschstörung und bleibt eine Herausforderung für die moderne Intensivmedizin. Extrakorporale Lungenunterstützungsverfahren werden dank technologischer Fortschritte in den letzten Jahren zunehmend zur Therapie der schweren respiratorischen Insuffizienz auf der Intensivstation angewendet. Der folgende Beitrag erläutert die Unterschiede extrakorporaler Lungenunterstützungssysteme, Indikationen zu deren Anwendung und potenzielle Komplikationen dieser Therapieform.
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Literatur
- 1 Pichler P. Antretter H. Dunser M. et al. Use of ECMO in adult patients with cardiogenic shock: a position paper of the Austrian Society of Cardiology. Med Klin Intensivmed Notfmed 2015; 110: 407-420
- 2 Fan E. Gattinoni L. Combes A. et al. Venovenous extracorporeal membrane oxygenation for acute respiratory failure: A clinical review from an international group of experts. Intensive Care Med 2016; 42: 712-724
- 3 Peek GJ. Mugford M. Tiruvoipati R. et al. Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial. Lancet 2009; 374: 1351-1363
- 4 Karagiannidis C. Brodie D. Strassmann S. et al. Extracorporeal membrane oxygenation: evolving epidemiology and mortality. Intensive Care Med 2016; 42: 889-896
- 5 Barbaro RP. Odetola FO. Kidwell KM. et al. Association of hospital-level volume of extracorporeal membrane oxygenation cases and mortality. Analysis of the extracorporeal life support organization registry. Am J Respir Crit Care Med 2015; 191: 894-901
- 6 Combes A. Brodie D. Bartlett R. et al. Position paper for the organization of extracorporeal membrane oxygenation programs for acute respiratory failure in adult patients. Am J Respir Crit Care Med 2014; 190: 488-496
- 7 Grimme I. Winter R. Kluge S. et al. Hypoxic cardiac arrest in pregnancy due to pulmonary haemorrhage. BMJ Case Rep 2012; DOI: 10.1136/bcr-2012-006741.
- 8 Serpa Neto A. Schmidt M. Azevedo LC. et al. Associations between ventilator settings during extracorporeal membrane oxygenation for refractory hypoxemia and outcome in patients with acute respiratory distress syndrome: a pooled individual patient data analysis: Mechanical ventilation during ECMO. Intensive Care Med 2016; 42: 1672-1684
- 9 Braune S. Kienast S. Hadem J. et al. Safety of percutaneous dilatational tracheostomy in patients on extracorporeal lung support. Intensive Care Med 2013; 39: 1792-1809
- 10 Fuehner T. Kuehn C. Hadem J. et al. Extracorporeal membrane oxygenation in awake patients as bridge to lung transplantation. Am J Respir Crit Care Med 2012; 185: 763-768
- 11 Langer T. Santini A. Bottino N. et al. "Awake" extracorporeal membrane oxygenation (ECMO): pathophysiology, technical considerations, and clinical pioneering. Crit Care 2016; 20: 150
- 12 Abrams DC. Prager K. Blinderman CD. et al. Ethical dilemmas encountered with the use of extracorporeal membrane oxygenation in adults. Chest 2014; 145: 876-882
- 13 Schaible T. Extracorporeal membrane oxygenation in children. Med Klin Intensivmed Notfmed 2015; 110: 438-444
- 14 Luyt CE. Brechot N. Demondion P. et al. Brain injury during venovenous extracorporeal membrane oxygenation. Intensive Care Med 2016; 42: 897-907
- 15 Kalbhenn J. Wittau N. Schmutz A. et al. Identification of acquired coagulation disorders and effects of target-controlled coagulation factor substitution on the incidence and severity of spontaneous intracranial bleeding during veno-venous ECMO therapy. Perfusion 2015; 30: 675-682
- 16 Paden ML. Conrad SA. Rycus PT. et al. Extracorporeal Life Support Organization Registry Report 2012. Asaio j 2013; 59: 202-210
- 17 Gray BW. Haft JW. Hirsch JC. et al. Extracorporeal life support: experience with 2000 patients. Asaio j 2015; 61: 2-7
- 18 Staudinger T. Extracorporeal lung support-news and future developments. Med Klin Intensivmed Notfmed 2016; DOI: 10.1007/s00063-016-0182-8.
- 19 John S. Willam C. Lung and kidney failure. Pathogenesis, interactions, and therapy. Med Klin Intensivmed Notfmed 2015; 110: 452-458
- 20 Allardet-Servent J. Castanier M. Signouret T. et al. Safety and Efficacy of Combined Extracorporeal CO2 Removal and Renal Replacement Therapy in Patients With Acute Respiratory Distress Syndrome and Acute Kidney Injury: The Pulmonary and Renal Support in Acute Respiratory Distress Syndrome Study. Crit Care Med 2015; 43: 2570-2581
- 21 Nierhaus A. Frings D. Braune S. et al. Interventional lung assist enables lung protective mechanical ventilation in acute respiratory distress syndrome. Minerva Anestesiol 2011; 77: 797-801
- 22 Terragni PP. Del Sorbo L. Mascia L. et al. Tidal volume lower than 6 ml/kg enhances lung protection: role of extracorporeal carbon dioxide removal. Anesthesiology 2009; 111: 826-835
- 23 Bein T. Weber-Carstens S. Goldmann A. et al. Lower tidal volume strategy (approximately 3 ml/kg) combined with extracorporeal CO2 removal versus 'conventional' protective ventilation (6 ml/kg) in severe ARDS: the prospective randomized Xtravent-study. Intensive Care Med 2013; 39: 847-856
- 24 Fitzgerald M. Millar J. Blackwood B. et al. Extracorporeal carbon dioxide removal for patients with acute respiratory failure secondary to the acute respiratory distress syndrome: a systematic review. Crit Care 2014; 18: 222
- 25 Burki NK. Mani RK. Herth FJ. et al. A novel extracorporeal CO(2) removal system: results of a pilot study of hypercapnic respiratory failure in patients with COPD. Chest 2013; 143: 678-686
- 26 Abrams DC. Brenner K. Burkart KM. et al. Pilot study of extracorporeal carbon dioxide removal to facilitate extubation and ambulation in exacerbations of chronic obstructive pulmonary disease. Ann Am Thorac Soc 2013; 10: 307-314
- 27 Braune SA. Kluge S. Extracorporeal lung support in patients with chronic obstructive pulmonary disease. Minerva Anestesiol 2013; 79: 934-943
- 28 Westhoff M. Schonhofer B. Neumann P. et al. Noninvasive Mechanical Ventilation in Acute Respiratory Failure. Pneumologie 2015; 69: 719-756
- 29 Kreppein U. Litterst P. Westhoff M. Hypercapnic respiratory failure. Pathophysiology, indications for mechanical ventilation and management. Med Klin Intensivmed Notfmed 2016; 111: 196-201
- 30 Kluge S. Braune SA. Engel M. et al. Avoiding invasive mechanical ventilation by extracorporeal carbon dioxide removal in patients failing noninvasive ventilation. Intensive Care Med 2012; 38: 1632-1639
- 31 Del Sorbo L. Pisani L. Filippini C. et al. Extracorporeal Co2 removal in hypercapnic patients at risk of noninvasive ventilation failure: a matched cohort study with historical control. Crit Care Med 2015; 43: 120-127
- 32 Braune S. Sieweke A. Brettner F. et al. The feasibility and safety of extracorporeal carbon dioxide removal to avoid intubation in patients with COPD unresponsive to noninvasive ventilation for acute hypercapnic respiratory failure (ECLAIR study): multicentre case-control study. Intensive Care Med 2016; 42: 1437-1444
- 33 Sklar MC. Beloncle F. Katsios CM. et al. Extracorporeal carbon dioxide removal in patients with chronic obstructive pulmonary disease: a systematic review. Intensive Care Med 2015; 41: 1752-1762