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Exp Clin Endocrinol Diabetes 2016; 124(10): 613-617
DOI: 10.1055/s-0042-111045
Article
© Georg Thieme Verlag KG Stuttgart · New York

Retinal Sensitivity in Patients with Type I Diabetes without Retinopathy or with Minor Retinal Changes

I. Pinilla
1   Department of Ophthalmology, Lozano Blesa University Hospital, Zaragoza, Spain
2   Department of Surgery, Gynecology and Obstetrics, University of Zaragoza, Zaragoza, Spain
3   Aragon Institute for Health Research, Zaragoza, Spain
,
A. Sanchez-Cano
3   Aragon Institute for Health Research, Zaragoza, Spain
4   Department of Applied Physics, University of Zaragoza, Zaragoza, Spain
,
A. Ferreras
2   Department of Surgery, Gynecology and Obstetrics, University of Zaragoza, Zaragoza, Spain
3   Aragon Institute for Health Research, Zaragoza, Spain
5   Department of Ophthalmology, Miguel Servet University Hospital, Zaragoza, Spain
,
J. Acha
6   Department of Endocrinology, Miguel Servet University Hospital, Zaragoza, Spain
,
D. Pérez-García
1   Department of Ophthalmology, Lozano Blesa University Hospital, Zaragoza, Spain
3   Aragon Institute for Health Research, Zaragoza, Spain
,
J. Ibañez-Alperte
1   Department of Ophthalmology, Lozano Blesa University Hospital, Zaragoza, Spain
3   Aragon Institute for Health Research, Zaragoza, Spain
,
E. Abecia
2   Department of Surgery, Gynecology and Obstetrics, University of Zaragoza, Zaragoza, Spain
3   Aragon Institute for Health Research, Zaragoza, Spain
5   Department of Ophthalmology, Miguel Servet University Hospital, Zaragoza, Spain
› Author Affiliations
Further Information

Publication History

received 17 February 2016
first decision 07 June 2016

accepted 23 June 2016

Publication Date:
22 September 2016 (online)

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Abstract

Objective: To evaluate the ability of short-wavelength automated perimetry (SWAP) for the detection of visual impairment in patients with type I diabetes without retinopathy or with minor retinal vascular changes.

Design: Comparative cross-sectional study.

Participants: 30 eyes of 30 healthy subjects and 73 eyes of 73 patients with type I diabetes mellitus were studied.

Methods: Ophthalmic examination of diabetic patients showed no retinopathy or minimal changes (less than 5 microaneurisms in each eye) with no previous laser treatment. All patients were examined by means of the SWAP 24-2 strategy. Mean Deviation (MD) and Pattern Standard Deviation (PSD) were compared between both groups.

Results: There were differences in the clusters of altered points between both groups (p=0.004). SWAP MD was lower in the diabetic group than in the controls (−2.89 dB vs. −0.20 dB, p<0.001). SWAP PSD also differed between both groups (2.50 dB in control group, 3.12 dB in the diabetic group, p=0.003). In the diabetic group, mean period from the onset of diabetes was 12.6±6.7 years and minimal vascular changes were observed in the retina of 18 eyes (24.7%), while 55 had no lesions (75.3%). No differences in SWAP changes were found between patients without and with minimal diabetic retinopathy.

Conclusions: Retinal sensitivity assessed by SWAP is depressed in patients with type I diabetes regardless of the presence of retinal vascular changes.

Key words

diabetes - retinopathy - microaneurisms - short-wavelength automated perimetry - visual field
 

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