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Diabetologie und Stoffwechsel 2016; 11(04): 298-300
DOI: 10.1055/s-0042-112386
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© Georg Thieme Verlag KG Stuttgart · New York

Regulation der Beta-Zellen der Langerhans’schen Inseln des Pankreas

Regulation of the beta cells in the islets of Langerhans
S. Baltrusch
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Publication History

Publication Date:
12 September 2016 (online)

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Zusammenfassung

Die Deutsche Diabetes Gesellschaft verlieh in diesem Jahr Frau Prof. Dr. Simone Baltrusch den Ferdinand-Bertram-Preis und ehrte sie damit für ihre wegweisenden und innovative Beiträge zur Beta-Zell Funktion. Ihr Arbeitsgebiet ist die Regulation der Beta-Zellen der Langerhans’schen Inseln des Pankreas und die zu einem Typ-2-Diabetes führenden Pathomechanismen; auf diesem Gebiet hat sie wichtige Beiträge (1) zum Glukosesenorenzym Glucokinase, (2) zur Rolle der mitochondrialen Dynamik in der Stimulus-Sekretionskopplung und (3) zur Steuerung der Insulingranulabewegung geleistet. In diesem Artikel fasst Frau Baltrusch ihre wichtigsten Publikationen zusammen.

Abstract

Prof. Dr. Simone Baltrusch received the Ferdinand-Bertram Award from the German Diabetes Assoziation in May 2016 for her outstanding contributions to improve the knowledge of beta cell function. Her research focus is on the regulation of the beta cells in the islets of Langerhans and the pathomechanisms resulting in type 2 diabetes. In this field she participated in the clarification of (1) the glucose sensor enzyme glucokinase, (2) the role of the mitochondrial dynamic in the stimulus secretion coupling and (3) the control of the insulin granule movement. In this article Dr. Baltrusch summarizes the most important findings of her publications.

Schlüsselwörter

Beta-Zellen - Glucokinase - Mitochondrien - Insulingranula

Key words

Beta cells - glucokinase - mitochondria - insulin granule
 

  • Literatur

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