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Dtsch Med Wochenschr 2017; 142(09): 687-688
DOI: 10.1055/s-0042-117210
Pro & Contra
© Georg Thieme Verlag KG Stuttgart · New York

Genetische Diagnostik bei familiärer Hypercholesterinämie – pro

Genetic Diagnosis in Familial Hypercholesterolemia – yes
Winfried März
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Publication History

Publication Date:
28 April 2017 (online)

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Nach der neuen europäischen Leitlinie zur kardiovaskulären Prävention sollen alle Personen unter 50 Jahren aufgrund klinischer Kriterien auf eine familiäre Hypercholesterinämie untersucht werden. Diese Kriterien sind aber weder ausreichend spezifisch noch sensitiv. Demgegenüber schafft die molekulare Diagnostik Sicherheit, Klarheit und solide Grundlagen für die Auswahl therapeutischer Optionen.

 

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