Aktuelle Neurologie, Table of Contents Aktuelle Neurologie 2017; 44(03): 200-202DOI: 10.1055/s-0043-100341 Kompetenznetz Multiple Sklerose © Georg Thieme Verlag KG Stuttgart · New York Aktuelles aus der Forschung T. Menge 1 Zentrum Neurologie und Neuropsychiatrie, LVR-Klinikum, Heinrich-Heine-Universität, Düsseldorf 2 Neurologische Klinik, Heinrich-Heine-Universität, Düsseldorf , G. Meyer zu Hörste 3 Klinik für Allgemeine Neurologie, Department für Neurologie, Universitätsklinikum Münster › Author Affiliations Recommend Article Abstract Buy Article Full Text References Literatur 1 Sawcer S, Hellenthal G, Pirinen M. et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 2011; 476: 214-219 2 Dendrou CA, Cortes A, Shipman L. et al. Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity. Sci Transl Med 2016; 8: 363ra149 3 Kreins AY, Ciancanelli MJ, Okada S. et al. Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome. J Exp Med 2015; 212: 1641-1662 4 Brändle SM, Obermeier B, Senel M. et al. Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins. Proc Natl Acad Sci U S A 2016; 113: 7864-7869 5 Ayoglu B, Mitsios N, Kockum I. et al. Anoctamin 2 identified as an autoimmune target in multiple sclerosis. Proc Natl Acad Sci U S A 2016; 113: 2188-2193 6 Hedstrom AK, Mowry EM, Gianfrancesco MA. et al. High consumption of coffee is associated with decreased multiple sclerosis risk; results from two independent studies. J Neurol Neurosurg Psychiatry 2016; 87: 454-460 7 Scalfari A, Neuhaus A, Daumer M. et al. Onset of secondary progressive phase and long-term evolution of multiple sclerosis. J Neurol Neurosurg Psychiatry 2014; 85: 67-75 8 Cree BA, Gourraud PA, Oksenberg JR. et al. Long-term evolution of multiple sclerosis disability in the treatment era. Ann Neurol 2016; 80: 499-510 9 Jokubaitis VG, Spelman T, Kalincik T. et al. Predictors of long-term disability accrual in relapse-onset multiple sclerosis. Ann Neurol 2016; 80: 89-100