Autoinflammatorische Erkrankungen als Differenzialdiagnose des Fiebers unklarer Genese

Abstract

Fever is the most leading symptom of autoinflammatory diseases (AID). Therefore, AID have to be considered in differential diagnosis concerning fever of unknown origin. Unspecific Inflammatory manifestations may lead to misinterpretations that possibly cause irreversible organ damage. Effective treatment options are available and imply profound diagnostics.

Autoinflammatorische Erkrankungen (AID) gehören zu den seltenen Erkrankungen. Sie gehen häufig mit Fieber einher und sind deshalb bei der Differenzialdiagnose des Fiebers unklarer Genese zu berücksichtigen. Begleitende unspezifische Entzündungsmanifestationen können allerdings zu Fehlinterpretationen führen – mit möglicherweise fatalen Folgen. Denn bleiben effektive Behandlungsmaßnahmen der AID aus, drohen irreversible Organschäden.

Schlüsselwörter

Fieber - autoinflammatorische Erkrankungen - Genetik - Colchicin - Interleukin-1-Inhibitoren

Key words

fever - autoinflammatory diseases - genetics - colchicine - interleukin-1-inhibitors

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