Molekulare Stratifizierung von kolorektalen Karzinomen – was hat Relevanz für die klinische Praxis?

Die Therapiemöglichkeiten des kolorektalen Karzinoms (KRK) und die Indikation zur systemischen Chemotherapie im adjuvanten Stadium werden zunehmend durch molekulare Marker beeinflusst. Hierbei ergänzen molekular pathologische Veränderungen zunehmend die etablierte TNM-Klassifikation und eröffnen bestimmten Patientengruppen neue Therapiestrategien.

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