Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000093.xml
Ernährung & Medizin 2017; 32(04): 153-157
DOI: 10.1055/s-0043-120771
DOI: 10.1055/s-0043-120771
wissen
Ernährung und Hormone
Situation und Prävention bei Frauen ab 50Further Information
Publication History
Publication Date:
19 December 2017 (online)
![](https://www.thieme-connect.de/media/eum/201704/lookinside/thumbnails/10-1055-s-0043-120771_kleine-gunk-1.jpg)
Zusammenfassung
Auch wenn viele Ärzte immer noch davor zurückschrecken, Altern als eine Krankheit zu betrachten, so bleibt doch festzuhalten: Biologisches Altern ist der wichtigste Risikofaktor für alle Erkrankungen, die in der westlichen Welt die Sterbestatistik anführen. Vor allem bei postmenopausalen Frauen beschleunigt der Hormonmangel zusätzlich diverse Alterungsprozesse. Allerdings ist dieser Verlauf durchaus nicht schicksalhaft. Durch Lebensstil und Ernährung sowie durch eine individualisierte Hormonersatztherapie ist eine effektive Prävention in vielen Fällen möglich (▶ Abb. [ 1 ]).
-
Literatur
- 1 Wang H, Dwyer-Lindgren L, Lofgren K. et al. Age-specific and sex-specific mortality in 187 countries 1970–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2010; 380: 2071-2094
- 2 Vos H, Bor H, Rangelrooij-Minkels M. et al. Multimorbidity in older women: the negative impact of specific combinations of chronic conditions on self-rated health. Eur J Gen Pract 2013; 1: 117-122
- 3 Rossouw JE, Anderson GL, Prentice RL. et al. Writing Group for the Women’s Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women’s Health Initiative randomized controlled trial. JAMA 2002; 288: 321-333
- 4 Rossouw JE, Prentice RL, Manson JE. et al. Postmenopausal hormone therapy and risk of cardiovaskular disease by age and years since menopause. JAMA 2007; 297: 1465-1477
- 5 Eckel R, Jakicic J, Ard J. et al. 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk; a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 2014; 129 (25 suppl. 2) 100-101
- 6 Neuhouser M, Wassertheil-Smoller S, Thomson C. et al. Multivitamin use and risk of cancer and cardiovascular disease in the Women’s Health Initiative cohorts. Arch Intern Med 2009; 169: 294-304
- 7 Manson JE, Chlebowski RT, Stefanick ML. et al. Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women’s Health Initiative randomized trials. JAMA 2013; 310: 1353-1368
- 8 Thomson C. Diet and breast cancer: understanding risks and benefits. Nutr Clin Pract 2012; 27: 636-650
- 9 Ziegler RG, Hoover RN, Pike MC. et al. Migration patterns and breast cancer risk in Asian-American women. J Natl Cancer Inst 1993; 85: 1819-1827
- 10 Cassidy A, Albertazzi P, Nielsen I. et al. Critical review of health effects of soyabean phyto-oestrogens in post-menopausal women. Proc Nutr Soc 2006; 65: 76-92
- 11 Hadji P, Klein S, Gothe H. et al. The epidemiology of osteoporosis – Bone Evaluation Study (BEST): an analysis of routine health insurance data. Dtsch Ärztebl Int 2013; 110: 52-57
- 12 Showers M, Crutchfield M, Bandekar R. et al. Bone mineral density and its change in pre- and perimenopausal white women: The Michigan Health Study. J Bone Min Res 1998; 13: 1134-1140
- 13 Malabanan A, Holick M. Vitamin D and bone health in postmenopausal women. J Women Health 2003; 12: 151-156
- 14 Prince M, Wimo A, Guerchet M. et al. On behalf of the Global Observatory for Ageing and Dementia Care. World Alzheimer Report 2015. The Global Impact of Dementia: An analysis of prevalence, incidence, cost, and trend. Alzheimer’s Disease International; 2015
- 15 Shumaker SA, Legault C, Rapp SR. et al. WHIMS Investigators. Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women. JAMA 2003; 189: 2651-2662
- 16 Gleason CE, Dowling NM, Wharton W. et al. Effects of hormone therapy on cognition and mood in recently postmenopausal women: Findings from the randomized, control KEEPS – Cognitive and Affective Study. PLoS Med; 2015 12.
- 17 Loef M, Walach H. Fruit, vegetables, and prevention of cognitive decline or dementia: a systematic review of cohort studies. J Nutr Health Aging 2012; 16: 626-630