Video Comment on Oscar V. Hernández Mondragón et al.

Oscar V. Hernández Mondragón et al. Long-term quality of life after peroral endoscopic myotomy remains compromised in patients with achalasia type III

This prospective cohort study demonstrates that peroral endoscopic myotomy (POEM) achieves significant long-term relief of dysphagia in patients with achalasia. Although dysphagia improvement was maintained, both integrated relaxation pressure and quality of life outcomes deteriorated over time, particularly in male patients with type 3 achalasia.