Toxoplasma gondii-Associated Bilateral Panuveitis and Encephalitis after Bone Marrow Transplantation

Background

Toxoplasmosis is one of the most common causes of infectious retinitis in both immunocompetent and immunocompromised individuals [1]. Toxoplasmic chorioretinitis in immunocompetent patients can be diagnosed clinically due to its typical presentation as a monocular, focal, necrotizing chorioretinitis lesion, sometimes adjacent to an older pigmented chorioretinal scar. However, in immunocompromised patients the clinical appearances of ocular toxoplasma infection can vary widely and thus be diagnostically challenging [2].

We report a patient, who presented with systemic worsening and bilateral panuveitis resulting in blindness two years after successful bone-marrow transplantation. Diagnostic testing confirmed ocular toxoplasmosis and consecutively, toxoplasmosis-related encephalitis was diagnosed.

• References

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