Download PDF
Aktuelle Rheumatologie 2018; 43(02): 135-142
DOI: 10.1055/s-0043-123464
Übersichtsarbeit
© Georg Thieme Verlag KG Stuttgart · New York

Rheumatische Erkrankungen bei Migranten

Rheumatic Diseases in Migrants
Ina Kötter
1   Internal Medicine 4, Rheumatology, Immunology, Nephrology, Asklepios Klinik Altona, Hamburg
› Author Affiliations
Further Information

Publication History

Publication Date:
06 March 2018 (online)

Also available at
    Permissions and Reprints

Zusammenfassung

Die Zuwanderung von Menschen aus anderen Ländern oder sogar von anderen Kontinenten stellt uns als Rheumatologen vor neue Herausforderungen. Obwohl alle entzündlich-rheumatischen Erkrankungen die hierzulande vorkommen, auch in den Heimatländern der Immigranten existieren, sind die Häufigkeiten unterschiedlich. Bei uns seltene Krankheitsbilder wie familiäres Mittelmeerfieber (FMF) oder M. Behcet sind v. a. in Nordafrika und im Mittelmeerraum oft häufiger als Spondyloarthritiden oder gar die RA. Das FMF ist zudem mit dem Auftreten einer Spondyloarthritis assoziiert, die dann häufig HLA-B27 negativ ist. Ebenso gibt es eine Assoziation mit dem M. Behcet. Auch das Rheumatische Fieber kommt v. a. in den afrikanischen Ländern noch häufig vor, während es in Europa fast ausgerottet ist. Zu beachten sind auch mögliche Differenzialdiagnosen wie rheumatische Symptome bei genetisch determinierten Anämien, oder bei Infektionen wie HIV, der Tuberkulose und Parasitosen, die allesamt in den Herkunftsländern der Migranten viel häufiger sind, als in Nordwesteuropa.

Abstract

The immigration of people from other countries, even more so from other continents, is a challenge for rheumatologists. Diseases such as familial Mediterranean fever (FMF) or Behcet’s disease (BD) are rare in Western Europe, whereas in North Africa and the Mediterranean countries they are even more common than rheumatoid arthritis (RA) or spondyloarthritis (SPA). Furthermore, FMF is associated with spondyloarthritis, which is mostly HLA-B27 negative, and it is also associated with BD. Rheumatic fever is still common especially in African, but also in some Mediterranean countries, whereas it is almost eradicated in Europe. Possible differential diagnoses such as rheumatic symptoms in genetically determined anaemia, or infections such as HIV, tuberculosis or parasitosis need to be considered, as they are all relatively common in the countries of origin of most immigrants in contrast to Germany and Northwest Europe.

Schlüsselwörter

Migranten - entzündlich-rheumatische Erkrankungen - Häufigkeiten - Probleme - Besonderheiten

Key words

immigrants - inflammatory rheumatic diseases - prevalences
 

  • Literatur

  • 1 http://www.bamf.de/SharedDocs/Anlagen/DE/Downloads/Infothek/Statistik/Asyl/aktuelle-zahlen-zu-asyl-dezember-2016. html?nn = 7952222 . Aktuelle Zahen zu Asyl. 2016
    PubMed
  • 2 Cakir N, Pamuk ON, Dervis E. et al. The prevalences of some rheumatic diseases in western Turkey: Havsa study. Rheumatol Int 2012; 32: 895-908
    CrossrefPubMedSearch in Google Scholar
  • 3 Davatchi F, Jamshidi AR, Banihashemi AT. et al. WHO-ILAR COPCORD Study (Stage 1, Urban Study) in Iran. J Rheumatol 2008; 35: 1384
    PubMedSearch in Google Scholar
  • 4 Moghimi N, Davatchi F, Rahimi E. et al. WHO-ILAR COPCORD study (stage 1, urban study) in Sanandaj, Iran. Clin Rheumatol 2015; 34: 535-543
    CrossrefPubMedSearch in Google Scholar
  • 5 Chaaya M, Slim ZN, Habib RR. et al. High burden of rheumatic diseases in Lebanon: a COPCORD study. Int J Rheum Dis 2012; 15: 136-143
    PubMedSearch in Google Scholar
  • 6 Akkoc N. Are spondyloarthropathies as common as rheumatoid arthritis worldwide? A review. Curr Rheumatol Rep 2008; 10: 371-378
    CrossrefPubMedSearch in Google Scholar
  • 7 Stolwijk C, van Onna M, Boonen A. et al. Global prevalence of spondyloarthritis: a systematic review and meta-regression analysis. Arthritis Care Res (Hoboken) 2016; 68: 1320-1331
    CrossrefPubMedSearch in Google Scholar
  • 8 Shapira Y, Agmon-Levin N, Shoenfeld Y. Geoepidemiology of autoimmune rheumatic diseases. Nat Rev Rheumatol 2010; 6: 468-476
    CrossrefPubMedSearch in Google Scholar
  • 9 Molokhia M, McKeigue PM, Cuadrado M. et al. Systemic lupus erythematosus in migrants from west Africa compared with Afro-Caribbean people in the UK. Lancet 2001; 357: 1414-1415
    CrossrefPubMedSearch in Google Scholar
  • 10 Tikly M, Navarra SV. Lupus in the developing world--is it any different?. Best Pract Res Clin Rheumatol 2008; 22: 643-655
    CrossrefPubMedSearch in Google Scholar
  • 11 Watad A, Tiosano S, Yahav D. et al. Behcet's disease and FMF: Two sides of the same coin or just an association? A cross-sectional study. Eur J Intern Med 2016;
    PubMedSearch in Google Scholar
  • 12 Livneh A, Langevitz P, Zemer D. et al. Criteria for the diagnosis of familial Mediterranean fever. Arthritis Rheum 1997; 40: 1879-1885 PubMed PMID: 9336425
    CrossrefPubMedSearch in Google Scholar
  • 13 Sari I, Birlik M, Kasifoglu T. Familial Mediterranean fever: An updated review. Eur J Rheumatol 2014; 1: 21-33
    CrossrefPubMedSearch in Google Scholar
  • 14 Ben-Chetrit E, Touitou I. Familial mediterranean Fever in the world. Arthritis Rheum 2009; 61: 1447-1453
    Search in Google Scholar
  • 15 Ebrahimi-Fakhari D, Schonland SO, Hegenbart U. et al. Familial Mediterranean fever in Germany: clinical presentation and amyloidosis risk. Scand J Rheumatol 2013; 42: 52-58
    CrossrefPubMedSearch in Google Scholar
  • 16 Giancane G, Ter Haar NM, Wulffraat N. et al. Evidence-based recommendations for genetic diagnosis of familial Mediterranean fever. Ann Rheum Dis 2015; 74: 635-641
    CrossrefPubMedSearch in Google Scholar
  • 17 Akkoc N, Sari I, Akar S. et al. Increased prevalence of M694V in patients with ankylosing spondylitis: additional evidence for a link with familial mediterranean fever. Arthritis Rheum 2010; 62: 3059-3063
    CrossrefPubMedSearch in Google Scholar
  • 18 Akar S, Soysal O, Balci A. et al. High prevalence of spondyloarthritis and ankylosing spondylitis among familial Mediterranean fever patients and their first-degree relatives: further evidence for the connection. Arthritis Res Ther 2013; 15: R21
    CrossrefPubMedSearch in Google Scholar
  • 19 Tasliyurt T, Yigit S, Rustemoglu A. et al. Common MEFV gene mutations in Turkish patients with Behcet's disease. Gene 2013; 530: 100-103
    CrossrefPubMedSearch in Google Scholar
  • 20 [Anonym] . Criteria for diagnosis of Behcet's disease. International Study Group for Behcet's Disease. Lancet 1990; 335: 1078-1080
    Search in Google Scholar
  • 21 International Team for the Revision of the International Criteria for Behcet's D. . The International Criteria for Behcet's Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol 2014; 28: 338-347
    CrossrefPubMedSearch in Google Scholar
  • 22 Mahr A, Belarbi L, Wechsler B. et al. Population-based prevalence study of Behcet's disease: differences by ethnic origin and low variation by age at immigration. Arthritis Rheum 2008; 58: 3951-3959
    CrossrefPubMedSearch in Google Scholar
  • 23 Mahr A, Maldini C. Epidemiology of Behcet's disease. Rev Med Interne 2014; 35: 81-89
    CrossrefPubMedSearch in Google Scholar
  • 24 Papoutsis NG, Abdel-Naser MB, Altenburg A. et al. Prevalence of Adamantiades-Behcet's disease in Germany and the municipality of Berlin: results of a nationwide survey. Clin Exp Rheumatol 2006; 24: S125
    PubMedSearch in Google Scholar
  • 25 Zouboulis CC. Epidemiology of Adamantiades-Behcet's disease. Ann Med Interne (Paris) 1999; 150: 488-498
    PubMedSearch in Google Scholar
  • 26 Kotter I, Vonthein R, Gunaydin I. et al. Behcet's disease in patients of German and Turkish origin – a comparative study. Adv Exp Med Biol 2003; 528: 53-58
    PubMedSearch in Google Scholar
  • 27 Gewitz MH, Baltimore RS, Tani LY. et al. Revision of the Jones Criteria for the diagnosis of acute rheumatic fever in the era of Doppler echocardiography: a scientific statement from the American Heart Association. Circulation 2015; 131: 1806-1818
    CrossrefPubMedSearch in Google Scholar
  • 28 Tibazarwa KB, Volmink JA, Mayosi BM. Incidence of acute rheumatic fever in the world: a systematic review of population-based studies. Heart 2008; 94: 1534-1540
    CrossrefPubMedSearch in Google Scholar
  • 29 Yildirim A, Aydin A, Demir T. et al. Acute rheumatic fever: a single center experience with 193 clinical cases. Minerva Pediatr 2016; 68: 134-142
    PubMedSearch in Google Scholar
  • 30 Zur B. Increase in genetically determined anemia as a result of migration in Germany. Internist (Berl) 2016; 57: 444-451
    CrossrefPubMedSearch in Google Scholar
  • 31 Muller SA, Amoah SK, Meese S. et al. High prevalence of anaemia among African migrants in Germany persists after exclusion of iron deficiency and erythrocyte polymorphisms. Trop Med Int Health 2015; 20: 1180-1189
    CrossrefPubMedSearch in Google Scholar
  • 32 Hughes M, Akram Q, Rees DC. et al. Haemoglobinopathies and the rheumatologist. Rheumatology (Oxford) 2016; 55: 2109-2118
    CrossrefPubMedSearch in Google Scholar
  • 33 Walker UA, Tyndall A, Daikeler T. Rheumatic conditions in human immunodeficiency virus infection. Rheumatology (Oxford) 2008; 47: 952-959
    CrossrefPubMedSearch in Google Scholar
  • 34 Iordache L, Launay O, Bouchaud O. et al. Autoimmune diseases in HIV-infected patients: 52 cases and literature review. Autoimmun Rev 2014; 13: 850-857
    CrossrefPubMedSearch in Google Scholar
  • 35 Cantini F, Nannini C, Niccoli L. et al. Guidance for the management of patients with latent tuberculosis infection requiring biologic therapy in rheumatology and dermatology clinical practice. Autoimmun Rev 2015; 14: 503-509
    CrossrefPubMedSearch in Google Scholar
  • 36 Jellis JE. Bacterial infections: bone and joint tuberculosis. Baillieres Clin Rheumatol 1995; 9: 151-159
    CrossrefPubMedSearch in Google Scholar
  • 37 Dinser R, Frerix M, Muller-Ladner U. Clinical presentation of tuberculosis in routine practice. Z Rheumatol 2012; 71: 711-716
    CrossrefPubMedSearch in Google Scholar
  • 38 Pigrau-Serrallach C, Rodriguez-Pardo D. Bone and joint tuberculosis. Eur Spine J 2013; 22 (Suppl. 04) 556-566
    CrossrefPubMedSearch in Google Scholar
  • 39 Abdulaziz S, Almoallim H, Ibrahim A. et al. Poncet's disease (reactive arthritis associated with tuberculosis): retrospective case series and review of literature. Clin Rheumatol 2012; 31: 1521-1528
    CrossrefPubMedSearch in Google Scholar
  • 40 Sharma A, Pinto B, Dogra S. et al. A case series and review of Poncet's disease, and the utility of current diagnostic criteria. Int J Rheum Dis 2016; 19: 1010-1017
    CrossrefPubMedSearch in Google Scholar
  • 41 Keat A. TB or not TB?: That is the question. Br J Rheumatol 1993; 32: 769-771
    CrossrefPubMedSearch in Google Scholar
  • 42 Stich A. [Frequent infectious diseases in migrants]. Internist (Berl) 2016; 57: 409-415
    CrossrefPubMedSearch in Google Scholar
  • 43 Folsch UR, Hasenfuss G, Spies HF. et al. [Flight and migration: A challenge for medicine in Germany]. Internist (Berl) 2016; 57: 822-830
    CrossrefPubMedSearch in Google Scholar
  • 44 Kellner U, Halder C, Litschi M. et al. Pain and psychological health status in chronic pain patients with migration background--the Zurich study. Clin Rheumatol 2013; 32: 189-197
    CrossrefPubMedSearch in Google Scholar
  • 45 El-Mansoury TM, Taal E, Abdel-Nasser AM. et al. Loneliness among women with rheumatoid arthritis: a cross-cultural study in the Netherlands and Egypt. Clin Rheumatol 2008; 27: 1109-1118
    CrossrefPubMedSearch in Google Scholar